DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and masp2

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001011037.1	Gene:	masp2 / 496446	XenbaseID:	XB-GENE-1007491	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	458	Identity:	122/458 - (26%)
Similarity:	189/458 - (41%)	Gaps:	109/458 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 DPVICCTEPRYNPVTERPRN-PFFPSESTFIGPQPPPEVPDNPF-LIPTPRTTTTTTTTTPAPIP 149
            ||::             ||| .|.|.:.|::.........|..| |:...||..:.|.|.   :|
Frog   301 DPIL-------------PRNGNFIPDQKTYVAGNHLSLTCDKGFVLLENARTIPSFTMTC---LP 349

  Fly   150 DTSAAPLIEPRGTVCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQ------ 208
            |          ||.    |.|...|: |..|.: .:::.:.:.....|..:...|:|.|
Frog   350 D----------GTW----DKKLPKCI-IVNCGN-PDDIENGTYSFVTAKEVTLYNSVVQYNCTEP 398

  Fly   209 -----NKGTQVCCPTG--QGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCG----STVGYFKKIV 262
                 .||...|...|  :.|.:....|...||               .||    :..|   :||
Frog   399 YYIKEGKGEYRCGADGFWEDIESEKKTPPICVP---------------DCGKRKPAAAG---RIV 445

  Fly   263 GGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI--RQDLQFVRLGEHDLSTDT 325
            |||.:..|.:||...:..::..|     ||.|:....:|||||.:  ..||..:.:....|||.
Frog   446 GGEFANVGEFPWQVFINANNERG-----GGALLLDNWILTAAHVVYSYDDLSSILIKMGFLSTQ- 504

  Fly   326 ETGHVDINIAR-----YVSHPDYNRRNGRSDMAILYLERNVEFTSK-IAPICLP------HTANL 378
                 |.|..|     ...|..|...:..:|:|::.|:..|..:.: |..||||      |.::.
Frog   505 -----DSNYIRGWPEAVFIHEGYKPGHYNNDIALIKLKNKVPLSEESILGICLPTKEKSYHISHK 564

  Fly   379 RQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAK-EKRYFSADQFDKAVLCA 442
            ...::||   .|||||.| |...|::.|..:::.|.|:..|...||| :.:|...:.    ::||
Frog   565 DDDNHVG---LVAGWGLT-EAQRSSRKLRFVEVNIVDHSTCKAEYAKLDAQYIVTEN----MICA 621

  Fly   443 GVLSGGKDTCQGDSGGPL--MLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQ 505
            |...|.||:|.|||||.|  |..|    ..::::.|:||:|:||......|||:....::|||.:
Frog   622 GFEIGVKDSCAGDSGGALAFMNAE----SKKWFVGGIVSWGVGCGVARQYGVYTKVTNYLDWIEK 682

  Fly   506 QVQ 508
            .:|
Frog   683 TIQ 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829	2/5 (40%)
		CLIP	164..216	CDD:288855	11/62 (18%)
		Tryp_SPc	260..503	CDD:214473	80/259 (31%)
		Tryp_SPc	261..503	CDD:238113	80/258 (31%)
masp2	NP_001011037.1	CUB	30..139	CDD:238001
		FXa_inhibition	145..180	CDD:317114
		CUB	184..294	CDD:238001
		CCP	299..361	CDD:153056	21/89 (24%)
		CCP	365..430	CDD:153056	11/65 (17%)
		Tryp_SPc	443..680	CDD:214473	80/259 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910