DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP010015

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_001238092.2	Gene:	AgaP_AGAP010015 / 4577984	VectorBaseID:	AGAP010015	Length:	239	Species:	Anopheles gambiae

Alignment Length:	243	Identity:	66/243 - (27%)
Similarity:	107/243 - (44%)	Gaps:	37/243 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 KIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQFVRLGEHDLSTD 324
            :|:.|.......:|:|..:.::|    .|.|.|.:||..|||:..:|.  ::...::..:...|.
Mosquito     9 RILNGLKVNPERYPFIVNIYFED----QFLCSGNIITPSHVLSLEYCF--EIFVFQMSIYGGGTS 67

  Fly   325 TETGHVDINIARYVSHPDYNRRNGRS--DMAILYLERNV-EFTSKIAPICLPHTANLRQKSYV-- 384
            ..:|.:.|.:.:...||::..|.|||  |:|::.:..|. :..:.:|.|.|       |.|.|
Mosquito    68 PLSGGISIPVNKITIHPNFEYRYGRSDFDVAVISVPINTFQGMANMASIAL-------QTSEVLP 125

  Fly   385 GYMPFVAGWGKTMEGGESAQVLNELQ---IPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLS 446
            |...:|.|||.:...|...  ||.|.   :.|.....|.:|:|......:::.. .|..|.||
Mosquito   126 GSRCYVIGWGVSKIFGPID--LNGLHYGTMNIVSQSACSRSWASVNENVTSNMI-CAKYCFGV-- 185

  Fly   447 GGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYS 494
               |.|.||.||||:......|     :||...|  ||.:.| |.|::
Mosquito   186 ---DICYGDLGGPLVCDGKLTG-----IIGYTEY--GCTKNN-PAVFT 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	66/243 (27%)
		Tryp_SPc	261..503	CDD:238113	66/242 (27%)
AgaP_AGAP010015	XP_001238092.2	Tryp_SPc	9..224	CDD:214473	66/243 (27%)
AgaP_AGAP010015	XP_001238092.2	Tryp_SPc	10..235	CDD:238113	66/242 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910