DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP012269

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_001238284.2	Gene:	AgaP_AGAP012269 / 4577485	VectorBaseID:	AGAP012269	Length:	649	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	74/285 - (25%)
Similarity:	119/285 - (41%)	Gaps:	40/285 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   241 PRRLLNVEEGCGS-TVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAA 304
            |.||.     ||. .|.....:..|..::.|.|||.|.:.:.......:.|||::|....:||||
Mosquito    25 PNRLT-----CGKRRVKTIHLVHNGIDAKPGHWPWHAAIFHRKGDQMDYACGGSIIDENTILTAA 84

  Fly   305 HCIRQDLQF------------VRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYL 357
            ||:     |            |.||...|...:|... :..:...:.||.||.....:|:|::.|
Mosquito    85 HCV-----FLVNGLLPVSRISVHLGRVHLKEVSEFVQ-EHTVQELIVHPGYNSSRFVNDIALIKL 143

  Fly   358 ERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQS 422
            ..::..:..:.|:|| .|.:..|:..||....:.|:|...:...|.| |.:..|.:.|...|:
Mosquito   144 TGSITMSEFVQPVCL-WTMDKNQELIVGKTGTLVGFGLNEQDVVSEQ-LKQASIGVVDALTCI-- 204

  Fly   423 YAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSY-----GI 482
              |..|...|:|....:.|.|..| ....|.|||||.|.    :..:.::::.||||:     ..
Mosquito   205 --KSDRLSFANQLTAEMFCGGGQS-NVSACNGDSGGGLF----FNVEGKWFVRGVVSFIPVRQRT 262

  Fly   483 GCARPNVPGVYSSTQYFMDWIIQQV 507
            |...|:....|:....::.||.|.:
Mosquito   263 GLCDPSKYTAYADVAKYLGWIDQYI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	65/259 (25%)
		Tryp_SPc	261..503	CDD:238113	65/258 (25%)
AgaP_AGAP012269	XP_001238284.2	Tryp_SPc	41..285	CDD:238113	67/260 (26%)
		Tryp_SPc	43..283	CDD:214473	65/256 (25%)
		Tryp_SPc	418..636	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910