DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CG9737

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	415	Identity:	126/415 - (30%)
Similarity:	181/415 - (43%)	Gaps:	99/415 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 DTKPGNCVEIKECASLLNELRSRSQDATFANFLR-----ASNAVCQNKGTQ---VCCP-TGQGIT 223
            :||.|.|:|:..|.:.|....:.:..|...|||:     ....|.:.:|:.   |||| .||...
  Fly    33 ETKRGVCLEVSRCKAYLQVRNATNLPAEKVNFLKKVQCEVEQQVSEAQGSYESLVCCPANGQDYL 97

  Fly   224 NTTPAPSQIVPK---------NTDEIPRRLLNVEEG--------CGSTVGYFKKIVGGEVSRKGA 271
            ......|:...:         ...::.||:..||..        ||..|  ..:|.|||::....
  Fly    98 FPVLQFSKFEYRRFLDVTARFKRKKLKRRIQTVEPSSGFNLLNECGKQV--TNRIYGGEIAELDE 160

  Fly   272 WPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI-------RQDLQFVRLGEHDLSTDTE--- 326
            :||:|||.|   :.:.:.|.|.||..||:||||||:       ||.|:.|||||.::.|:.:
  Fly   161 FPWLALLVY---NSNDYGCSGALIDDRHILTAAHCVQGEGVRDRQGLKHVRLGEFNVKTEPDCIE 222

  Fly   327 --------TGHVDINIARYVSHPDYNRRNG--RSDMAILYLERNVEFTSKIAPICLPHTA---NL 378
                    ...:||...:...||:|...:.  .:|:||:.|:..|.||..:.|||||:.:   .|
  Fly   223 EPNYLSCADAALDIAYEKIHVHPEYKEFSNYKYNDIAIIRLKHPVSFTHFVMPICLPNKSEPLTL 287

  Fly   379 RQKSYVGYMPFVAGWGKTMEGGESAQVLN------------ELQIPIYDNKVCVQSYAKEKRYFS 431
            .:    |.|..|:|||:|       .:.|            :|:||...|:.|    .|....|.
  Fly   288 AE----GQMFSVSGWGRT-------DLFNKYFINIHSPIKLKLRIPYVSNENC----TKILEGFG 337

  Fly   432 ADQFDKAVLCAGVLSG--GKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGI-GCARPNVPGVY 493
            .....|.: |||   |  .||||.||||||||..:  :...|:...||||||. .|.....|.||
  Fly   338 VRLGPKQI-CAG---GEFAKDTCAGDSGGPLMYFD--RQHSRWVAYGVVSYGFTQCGMAGKPAVY 396

  Fly   494 SSTQYFMDWI---------IQQVQD 509
            ::...:.|||         .||.||
  Fly   397 TNVAEYTDWIDSVVQQRKKSQQTQD 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	14/55 (25%)
		Tryp_SPc	260..503	CDD:214473	93/280 (33%)
		Tryp_SPc	261..503	CDD:238113	93/279 (33%)
CG9737	NP_651783.1	CLIP	28..89	CDD:288855	14/55 (25%)
		Tryp_SPc	149..406	CDD:214473	93/280 (33%)
		Tryp_SPc	150..409	CDD:238113	95/282 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	2.920