DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Tmprss9

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	406	Identity:	117/406 - (28%)
Similarity:	161/406 - (39%)	Gaps:	91/406 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 RTTTTTTTTTPAPIPDTSAAPLIEPRGTVCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANF 199
            |..|::|...|:..|.|:||.||.|..|..                       |..:..||....
Mouse   997 RPHTSSTRLIPSEPPKTTAAGLIIPEATTS-----------------------RLATPRATIRVT 1038

  Fly   200 LRASNAVCQNKGTQVCCPTGQGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCG-STVGYFKKIVG 263
            .|..|.....:.|     |.:|.|....||...:..:..:           || :..|...:|||
Mouse  1039 TRPLNTTLSARST-----TTRGQTAAPSAPGTTIHSHLPD-----------CGLAPPGALTRIVG 1087

  Fly   264 GEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI---RQDLQFVR-LGEHDLSTD 324
            |..:..|.|||...|..   .....:||..|:..|.:|:||||.   ...:|:.. ||...||:
Mouse  1088 GSAASLGEWPWQVSLWL---RRREHRCGAVLVAERWLLSAAHCFDIYGDPMQWAAFLGTPFLSS- 1148

  Fly   325 TETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPF 389
            || |.:: .:||...||.||......|:|:|.|...|..:..:.|||||..|    :...|....
Mouse  1149 TE-GQLE-RVARIYRHPFYNIYTLDYDVALLELAGPVRRSRLVRPICLPGPA----RPPDGARCV 1207

  Fly   390 VAGWGKTMEG--------------------------GESAQVLNELQIPIYDNKVCVQSYAKEKR 428
            :.|||...||                          |..|:.|.:..:.:...:.|        |
Mouse  1208 ITGWGSLREGGIHACVRRSPGGVGDTPHLHLSPDPTGSMARQLQKAAVRVLSEQTC--------R 1264

  Fly   429 YFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVY 493
            .|...|....:||||...||.|:|.||:||||...|| .||  :.|.||.|:|.||.||:.||||
Mouse  1265 RFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREP-SGQ--WVLTGVTSWGYGCGRPHFPGVY 1326

  Fly   494 SSTQYFMDWIIQQVQD 509
            :.....:.||.|.:|:
Mouse  1327 TRVAAVLGWIGQNIQE 1342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	6/51 (12%)
		Tryp_SPc	260..503	CDD:214473	87/272 (32%)
		Tryp_SPc	261..503	CDD:238113	87/271 (32%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113	87/271 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910