DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and CG16710

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_651167.3	Gene:	CG16710 / 42790	FlyBaseID:	FBgn0039101	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	118/381 - (30%)
Similarity:	176/381 - (46%)	Gaps:	103/381 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 CVEIKECASLLNELRSRSQDATFANFLRASNAVCQN-------KGTQ------VCCPT-GQGITN 224
            |:.:..|.|||..|:..       |...|..||.::       ||.:      :|||. |..:.|
  Fly    36 CISLARCTSLLPFLKPH-------NMTPAEKAVFEDRYCGYGPKGQELLDRVLICCPNMGHILPN 93

  Fly   225 TTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPF- 288
            |     ||                  ||..:..: :|.|||.::....||:||:.|...|.|.:
  Fly    94 T-----QI------------------CGPIMPAY-RIFGGEETQPNELPWMALILYAHRSRSVWN 134

  Fly   289 -----KCGGTLITARHVLTAAHCIR---QDLQFVRLGEHDLSTDTE------------TGHVDIN 333
                 :|.|:|||.|:|||||||:|   .||:.||||||::.::.:            ..|::|:
  Fly   135 ERLVSRCAGSLITNRYVLTAAHCLRITGLDLRRVRLGEHNILSNPDCVTHINGREHCAPEHLEID 199

  Fly   334 IARYVSHPDYNRRNGR--SDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKT 396
            :...:.|..|.....|  :|:|:|.|:..|.:|::|.|||:.........|:..:...:||||.:
  Fly   200 VDLSIKHRHYMVFEERPYNDIALLRLKFPVRYTAQIKPICVQLDYIFSNPSFSNHKLQIAGWGLS 264

  Fly   397 MEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQ---------FDKAV-LCAGVLSGGKDT 451
            .:.|             |.| |.:|:|...:   :||:         .||.. :|||.| ||.||
  Fly   265 HKQG-------------YSN-VLLQAYVNGR---NADECSLSEPSLGLDKETHICAGNL-GGNDT 311

  Fly   452 CQGDSGGPLM-LPEPYQGQLRF-YLIGVVSYGIG-CARPNVPGVYSSTQYFMDWII 504
            |:|||||||| :.|  :|...| ||.|:.|||.. |...  |..|:.|..|::||:
  Fly   312 CKGDSGGPLMAIME--RGDEEFVYLAGITSYGYSQCGYG--PAAYTKTSKFVEWIL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	12/54 (22%)
		Tryp_SPc	260..503	CDD:214473	94/278 (34%)
		Tryp_SPc	261..503	CDD:238113	94/277 (34%)
CG16710	NP_651167.3	CLIP	35..84	CDD:288855	12/54 (22%)
		Tryp_SPc	105..362	CDD:214473	94/278 (34%)
		Tryp_SPc	106..362	CDD:238113	94/277 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920