DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Sb

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster

Alignment Length:	519	Identity:	146/519 - (28%)
Similarity:	212/519 - (40%)	Gaps:	146/519 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 TEPRYN----------PVTERPRNPFFPSESTFI---GPQPPPEVPDN----------------- 127
            |:||..          |:..||..|..|::...:   .|.|||.||.:
  Fly   312 TKPRPTGWTKPGIVNLPMPARPSKPSKPTKKPIVYDRTPPPPPSVPPSTSTSTTSTSLIWPAQTH 376

  Fly   128 ---------PFLIP----------------------TPRTTTTTTTTTPAPIPDTSAAPLIEPRG 161
                     |.|.|                      |..||||||||.....|.|:.      |.
  Fly   377 PPQPHRPTRPQLSPGTSLAASSSSHWPSSTTSTTSSTTSTTTTTTTTRRTTTPTTTT------RR 435

  Fly   162 TVCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQVCCP------TGQ 220
            |....| |:|                ..|...||.:    :|.:...:|......|      :..
  Fly   436 TTTNKP-TRP----------------YQRPTTATSS----SSTSTTSSKTPTTTRPISSSSSSSS 479

  Fly   221 GITNTTPAPSQIVPK---------NTDEIP-------------RRLLNVEEGCG--STVGYFKKI 261
            ||..::..|:|...:         .|:||.             :.:......||  :......:|
  Fly   480 GIVTSSQRPTQPTHRTPVLATSGIETNEISDSSIPDAGALGHVKTISAARSECGVPTLARPETRI 544

  Fly   262 VGGEVSRKGAWPW------IALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQF----VRL 316
            |||:.:..|.|||      .:..|:    .|..:|||.||....:.||.||: .||..    :|:
  Fly   545 VGGKSAAFGRWPWQVSVRRTSFFGF----SSTHRCGGALINENWIATAGHCV-DDLLISQIRIRV 604

  Fly   317 GEHDLS-TDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQ 380
            ||:|.| ...:..:::..:|:.|.||.|:......|:|::.||:.:||...::|||||.|.:|
  Fly   605 GEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETDSL-- 667

  Fly   381 KSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRY-FSADQFDKAVLCAGV 444
              .:|....|.|||:..|||....||.|:.:||..|..|...:.:..|. |..|.|    ||||.
  Fly   668 --LIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIF----LCAGY 726

  Fly   445 LSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQ 508
            .:||:|:|||||||||. .:...|  ||:|.|::|:|||||..|:|||.:....|..||::.|:
  Fly   727 ETGGQDSCQGDSGGPLQ-AKSQDG--RFFLAGIISWGIGCAEANLPGVCTRISKFTPWILEHVR 787

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829	146/519 (28%)
		CLIP	164..216	CDD:288855	8/51 (16%)
		Tryp_SPc	260..503	CDD:214473	95/254 (37%)
		Tryp_SPc	261..503	CDD:238113	95/253 (38%)
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	95/254 (37%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	97/256 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010