DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and ea

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	117/374 - (31%)
Similarity:	178/374 - (47%)	Gaps:	48/374 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 CRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQVCCPT--GQGITNTT 226
            |..|:.:...|:.:::|..|...|.:.....|...:|..|.....|....:|||.  .:..:.||
  Fly    37 CITPNRERALCIHLEDCKYLYGLLTTTPLRDTDRLYLSRSQCGYTNGKVLICCPDRYRESSSETT 101

  Fly   227 PAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSP-FKC 290
            |.|...|..|:      ||.:...||:.:.  .:|.||..::...:||:||:.|....|.. ..|
  Fly   102 PPPKPNVTSNS------LLPLPGQCGNILS--NRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHC 158

  Fly   291 GGTLITARHVLTAAHCIRQD-------LQFVRLGEHDLST------------DTETGHVDINIAR 336
            ||:||:.|:|:||:||:...       |..|||||.|.:|            |....|:|:.:.|
  Fly   159 GGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVER 223

  Fly   337 YVSHPDY--NRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEG 399
            .:.||||  ..:|..:|:|:|.|.:.||:|..:.|||||...|||..::.|....|||||||.:.
  Fly   224 TIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQL 288

  Fly   400 GESAQVLNELQIPIYDNKVCVQSYAKEK---RYFSAD-QFDKAVLCAGVLSGGKDTCQGDSGGPL 460
            ..|...|          |..|:.:..::   .|.|.| ..:...:|||. ..|.|:|:|||||||
  Fly   289 SASNLKL----------KAAVEGFRMDECQNVYSSQDILLEDTQMCAGG-KEGVDSCRGDSGGPL 342

  Fly   461 MLPEPYQGQLRFYLIGVVSYG-IGCARPNVPGVYSSTQYFMDWIIQQVQ 508
            :..:..:....::|.||||:| ..|.....||||:....::|||...::
  Fly   343 IGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIE 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	10/51 (20%)
		Tryp_SPc	260..503	CDD:214473	92/269 (34%)
		Tryp_SPc	261..503	CDD:238113	92/268 (34%)
ea	NP_524362.2	CLIP	37..89	CDD:288855	10/51 (20%)
		Tryp_SPc	127..386	CDD:214473	92/269 (34%)
		Tryp_SPc	128..389	CDD:238113	94/271 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	2.920