DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CG3505

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	114/388 - (29%)
Similarity:	174/388 - (44%)	Gaps:	83/388 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 APIPDTSAAPLIEPRGTVCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNK 210
            |.:|..:....| |.|.|       .|:|:.|:||...:..|.|.:...:..|.||.:....:..
  Fly    20 AQLPPINCVAKI-PSGRV-------TGHCISIRECDYFMRILLSGNLSQSDRNLLRDNQCGVRGN 76

  Fly   211 GTQVCCPTGQGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWI 275
            ..|||||:..|:...|   ..::|.:..::..:..|..:                 :|...:||:
  Fly    77 DVQVCCPSTAGLGALT---HPLLPSDCGKVRWQRSNDTD-----------------TRIREFPWL 121

  Fly   276 ALLGYDDPSGSPFK---CGGTLITARHVLTAAHCIRQ----DLQF--VRLGEHDLST-------- 323
            ||:.|  ..|:..|   |||.||:.|:|||||||:.|    :||.  |||||.|.||
  Fly   122 ALIEY--TRGNQEKIHACGGVLISDRYVLTAAHCVAQAATSNLQITAVRLGEWDTSTNPDCQYHE 184

  Fly   324 -----DTETGHVDINIARYVSHPDYNR--RNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQK 381
                 |....:.||.|...:.||.|||  |...:|:|::.|....:....:.|||||: ..||..
  Fly   185 DSKVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLPN-KQLRAD 248

  Fly   382 SYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLS 446
            .....:..||||     ...|:|.:.:..:.|...:.|.:.||.::....|.:     ||.  |:
  Fly   249 ELEDLVTEVAGW-----QASSSQRMRKGYVTISSIEECQRKYASQQLRIQASK-----LCG--LT 301

  Fly   447 GGKDTCQGDSGGPLMLPEPYQGQLRF----YLI-GVVSYG-IGCARPNVPGVYSSTQYFMDWI 503
            ..:: |.|::||||||         |    ||: |:||:| :.|..|:.|.||:....::|||
  Fly   302 NSQE-CYGNAGGPLML---------FKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWI 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	12/51 (24%)
		Tryp_SPc	260..503	CDD:214473	87/272 (32%)
		Tryp_SPc	261..503	CDD:238113	87/271 (32%)
CG3505	NP_650380.2	CLIP	30..82	CDD:288855	16/59 (27%)
		Tryp_SPc	111..356	CDD:238113	89/286 (31%)
		Tryp_SPc	111..354	CDD:214473	87/284 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920