DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CG8870

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_731802.1	Gene:	CG8870 / 41645	FlyBaseID:	FBgn0038144	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	112/376 - (29%)
Similarity:	170/376 - (45%)	Gaps:	97/376 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 DTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGT-QVCCPTGQGITNTTPAPSQ 231
            ||:   ||.:.:|.      |:|:    ..|..|.:....:..|| :||||..:          .
  Fly    29 DTE---CVNLDKCP------RTRA----VMNSSRKNIIGLRRCGTNKVCCPKWE----------T 70

  Fly   232 IVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSG-----SPFKCG 291
            .:|.:|             ||.:   .:|...|::.....:||:|:|.|.:.:.     .| |||
  Fly    71 YLPHDT-------------CGQS---RRKPTKGKIPALNEFPWMAMLLYGNKNNLSQKLVP-KCG 118

  Fly   292 GTLITARHVLTAAHCIRQD-------LQFVRLGEHDLSTDTETG-----------HVDINIARYV 338
            |:||...:|||||||:...       |:.||||||:.||:.:..           :::|.:.:.:
  Fly   119 GSLINNWYVLTAAHCVEYPFMDYPYALKTVRLGEHNTSTNPDRAIVNGRRQYAPLYMEIEVDQII 183

  Fly   339 SHPDYNRRNGR---SDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVA-GWGKTMEG 399
            :|..:||  ||   :|:|::.|:..|.:|..|.|||||..    ||.......|.| || ..|..
  Fly   184 THEQFNR--GRRLINDIALVRLKFPVRYTRAIQPICLPRA----QKLAAHKRKFQASGW-PDMGQ 241

  Fly   400 GESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFD-KAVLCAGVLSGGKDTCQGDSGGPLMLP 463
            |.:::||....|......||..:|          .|: .:.:|||.|. |.||..|||||||| .
  Fly   242 GIASEVLLRSFIAERHPDVCKSNY----------DFNLGSQICAGGLD-GNDTSPGDSGGPLM-E 294

  Fly   464 EPYQGQLRF-YLIGVVSYGIGCARPNV-----PGVYSSTQYFMDWIIQQVQ 508
            ...:|::.. |..|::|||   .:|.|     |..|:.|.||.:||..::|
  Fly   295 TVIRGKVTLTYAAGIISYG---QKPCVLKTCKPAFYTKTSYFFEWIKSKLQ 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	12/48 (25%)
		Tryp_SPc	260..503	CDD:214473	90/276 (33%)
		Tryp_SPc	261..503	CDD:238113	89/275 (32%)
CG8870	NP_731802.1	Tryp_SPc	93..340	CDD:238113	90/269 (33%)
CG8870	NP_731802.1	Tryp_SPc	93..337	CDD:214473	88/266 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920