DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and Sp7

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	121/382 - (31%)
Similarity:	178/382 - (46%)	Gaps:	59/382 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 CRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVC-QNKGTQ--VCCPTGQGITN- 224
            ||.|:.|.|.|:.|.:|.|||:.::..........|||  |:.| ...|.|  |||.:.:...:
  Fly    31 CRNPNQKQGQCLSIYDCQSLLSVIQQSYVSPEDRTFLR--NSQCLDGVGRQPYVCCTSDRSFGSQ 93

  Fly   225 --TTPAPSQIVPKNTDEIPRRLLNVEEGCGSTV---------GYFKKIVGGEVSRKGAWPWIALL 278
              |:.||    |..|.....|..:.:.|.|:.:         .:..|:..|..:....:.|:|||
  Fly    94 EATSAAP----PPTTTSSSSRGQDGQAGLGNLLPSPPKCGPHSFSNKVYNGNDTAIDEFNWMALL 154

  Fly   279 GYDDPSG-SPFKCGGTLITARHVLTAAHCI-------RQDLQFVRLGEHDLSTDTETGHVD---- 331
            .|.|..| ....|||:||..|:|||||||:       ...|..|||||:|.|.|.:.  :|
  Fly   155 EYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVETEVGHLTTVRLGEYDTSKDVDC--IDDICN 217

  Fly   332 -----INIARYVSHPDYN--RRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPF 389
                 :.|.:...||.|:  .:|...|:|:|.|:|.|.....|.|:||| ..:.|.....|.:..
  Fly   218 QPILQLGIEQATVHPQYDPANKNRIHDIALLRLDRPVVLNEYIQPVCLP-LVSTRMAINTGELLV 281

  Fly   390 VAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGG---KDT 451
            |:|||:|....:|. :...|.:|:.|:..|.:.:|....:..:.|     ||.    ||   :|:
  Fly   282 VSGWGRTTTARKST-IKQRLDLPVNDHDYCARKFATRNIHLISSQ-----LCV----GGEFYRDS 336

  Fly   452 CQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQ 508
            |.||||||||.....|.   :|..||||:|..|.....||||:....:||||::.::
  Fly   337 CDGDSGGPLMRRGFDQA---WYQEGVVSFGNRCGLEGWPGVYTRVADYMDWIVETIR 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	19/54 (35%)
		Tryp_SPc	260..503	CDD:214473	90/264 (34%)
		Tryp_SPc	261..503	CDD:238113	89/263 (34%)
Sp7	NP_649734.2	CLIP	31..84	CDD:288855	19/54 (35%)
		Tryp_SPc	136..385	CDD:214473	90/264 (34%)
		Tryp_SPc	137..388	CDD:238113	91/266 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	2.920