DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and ela2

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001132936.1	Gene:	ela2 / 403061	ZFINID:	ZDB-GENE-041117-1	Length:	266	Species:	Danio rerio

Alignment Length:	274	Identity:	98/274 - (35%)
Similarity:	139/274 - (50%)	Gaps:	49/274 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 GCGSTVGYFK----KIVGGEVSRKGAWPWIALLGYDDPSGSPF--KCGGTLITARHVLTAAHCIR 308
            |||...  :|    ::|||...|..:|||.|.|.|.  |||.|  .||||||..:.||||||||.
Zfish    15 GCGQPT--YKPIDSRVVGGSDVRPNSWPWQASLQYQ--SGSSFYHTCGGTLIDKQWVLTAAHCIS 75

  Fly   309 QDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLP 373
            .....|.||:|:|...:|:|...|:.||.:.|.:::..|.|:|:|::.|...|.||.||:|.|||
Zfish    76 SRTYRVLLGKHNLPLSSESGSQAISPARIIVHENWDSYNIRNDIALIKLSTPVTFTDKISPACLP 140

  Fly   374 HTANLRQKSYVGYMP-----FVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSAD 433
            .:.::        :|     :|.|||:...||..|.:|.:..:||.|...|.:|          |
Zfish   141 DSGSI--------LPHNSPCYVTGWGRLWTGGPIADILQQALLPIVDQATCTKS----------D 187

  Fly   434 QFDKAV----LCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLR---FYLIGVVSYG--IGCARPNV 489
            .:...|    :|||. .|...:|.|||||||      ..|.|   :.:.|:||:|  :||..|..
Zfish   188 WWGNLVTDLMVCAGG-DGVVSSCNGDSGGPL------NCQRRDGTWDVHGIVSFGSSLGCNYPKK 245

  Fly   490 PGVYSSTQYFMDWI 503
            |.|::....::.||
Zfish   246 PSVFTRVSGYIPWI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	92/258 (36%)
		Tryp_SPc	261..503	CDD:238113	92/257 (36%)
ela2	NP_001132936.1	Tryp_SPc	27..259	CDD:214473	92/258 (36%)
ela2	NP_001132936.1	Tryp_SPc	28..262	CDD:238113	94/259 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910