DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Prss48

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001001650.1	Gene:	Prss48 / 368202	MGIID:	2685865	Length:	312	Species:	Mus musculus

Alignment Length:	283	Identity:	102/283 - (36%)
Similarity:	141/283 - (49%)	Gaps:	46/283 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 NVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQD 310
            |::..||..| :..:||||:.:..|.|||...|.:|    ....|||:||:...||||||||::.
Mouse    26 NLQSVCGRPV-HTGRIVGGQDAALGRWPWQVSLRFD----YTHSCGGSLISDHWVLTAAHCIKKT 85

  Fly   311 ----LQFVRLGEHD---LSTDTETGHVDINIARYVSH---PDYNRRNGRSDMAILYLERNVEFTS 365
                |..|.||..|   .||..|         .|||.   || ..|:..:|:|:|.|...|.|:|
Mouse    86 WYSFLYSVWLGSIDREYSSTGKE---------YYVSRIAIPD-KHRHTEADIALLKLSSRVTFSS 140

  Fly   366 KIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSY------- 423
            .|.|||||   |:.::..|....:|.|||:..| |.....|.||::|:..::.|.|.|
Mouse   141 VILPICLP---NISKQLTVPASCWVTGWGQNQE-GHYPSTLQELEVPVISSEACEQLYNPIGVFL 201

  Fly   424 AKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPN 488
            ...:|....|.|     |||.....||:|:|||||||..  ...|..|  |:||||:|:.|.: :
Mouse   202 PDLERVIKEDMF-----CAGERQSRKDSCKGDSGGPLSC--HIDGVWR--LMGVVSWGLECGK-D 256

  Fly   489 VPGVYSSTQYFMDWIIQQVQDTP 511
            :||||::..|:..||...:...|
Mouse   257 LPGVYTNVTYYQKWISAIISRAP 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	95/259 (37%)
		Tryp_SPc	261..503	CDD:238113	95/258 (37%)
Prss48	NP_001001650.1	Tryp_SPc	39..271	CDD:214473	95/259 (37%)
Prss48	NP_001001650.1	Tryp_SPc	40..274	CDD:238113	97/261 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910