DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	114/397 - (28%)
Similarity:	176/397 - (44%)	Gaps:	91/397 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 PRGTVCRG-----------------PDTKPGNCVEIKECASLLNEL---RSRSQDATFANFLRA- 202
            |||.:|.|                 |: |||..|.:.:..|.|..|   |.......|.||..|
  Rat   113 PRGQMCDGHLDCASGEDEEHCVKNFPE-KPGVTVRLSKDRSTLQVLDAARGTWASVCFDNFTEAL 176

  Fly   203 SNAVCQNKGTQVCCPTGQGITNTTPA-------PSQI-----VPKNTDEIPRRLLNVEEGC--GS 253
            :...|:..|           .|:.||       |:|.     |..|:.|:  ::.|....|  ||
  Rat   177 AKTACRQMG-----------YNSQPAFGPVEMGPNQTLLVTPVTGNSQEL--QMQNGSRSCLSGS 228

  Fly   254 TVGY----------FKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIR 308
            .|..          ..::|||..:...:|||...:.|:    ....|||:::....:||||||.|
  Rat   229 LVSLRCLDCGKSLKTTRVVGGVEASADSWPWQVSIQYN----KQHVCGGSILDHHWILTAAHCFR 289

  Fly   309 QDLQF----VRLGEHDLSTDTETGHVDINIAR-YVSHPDYNRRNGRSDMAILYLERNVEFTSKIA 368
            :.|..    ||.|.:.|....     .:.:|: :::.|: ..:....|:|::.|:..:.|:..:.
  Rat   290 KYLDVSSWKVRAGSNKLGNSP-----SLPVAKIFIAEPN-PLQPKEKDIALVKLKMPLTFSGSVR 348

  Fly   369 PICLPHTANLRQKSYVGYMP-FVAGWGKTME-GGESAQVLNELQIPIYDNKVCVQSYAKEKRYFS 431
            |||||.:    .:..:..|| :|.|||.|.| ||:.:..|.:..:.:.|:..|....|.:
  Rat   349 PICLPFS----DEELIPTMPVWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQ----- 404

  Fly   432 ADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSST 496
             .:....:||||...|||||||||||||||    |... ::.::|:||:|.||..|:.||||:..
  Rat   405 -GEVTAGMLCAGTPQGGKDTCQGDSGGPLM----YHYD-KWQVVGIVSWGYGCGSPSTPGVYTKV 463

  Fly   497 QYFMDWI 503
            ..::|||
  Rat   464 TAYLDWI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	17/72 (24%)
		Tryp_SPc	260..503	CDD:214473	79/249 (32%)
		Tryp_SPc	261..503	CDD:238113	79/248 (32%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060	5/19 (26%)
		SRCR_2	149..238	CDD:413346	23/101 (23%)
		Tryp_SPc	245..470	CDD:214473	79/249 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910