DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and flz

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	133/413 - (32%)
Similarity:	189/413 - (45%)	Gaps:	80/413 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 PTPRTTT----------TTTTTTPAPIPDTSAAPLIEPRGTVCRGPDTKPGNCVEIKECASLLNE 186
            |..|.||          :|||..||....|.||.:.    |..|.|.||...           ..
  Fly  1313 PVTRVTTKAPNKKTSAVSTTTRKPATRRTTVAAKVT----TTTRRPATKKPT-----------RR 1362

  Fly   187 LRSRSQDATFANFLRASNAVCQNKGTQVCCPT------GQGIT----------------NTTPAP 229
            :.|..:..|.::...|.:.:...:..:...|.      .||.|                .|.|.|
  Fly  1363 VSSTVKTTTVSSARPADDEIVDEEDEEDVNPNPSDNEIDQGATLSSYGGANGRKIHSTSRTLPTP 1427

  Fly   230 SQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSG--SPFKCGG 292
            :......:.|...| .:|:.|         :||||:.|..||:||..|:......|  :..||||
  Fly  1428 NLAFHSPSTECGVR-PHVKSG---------RIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGG 1482

  Fly   293 TLITARHVLTAAHC---IRQDLQFVRLGEHDLSTDTETGH-VDINIARYVSHPDYNRRNGRSDMA 353
            .|||:|:|:|||||   ....|..| :||.|:|.|.|:.. |..|:.|.:.|..|:.....:|:|
  Fly  1483 VLITSRYVITAAHCQPGFLASLVAV-MGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLA 1546

  Fly   354 ILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKV 418
            :|.|:..|:|.:.|.|||:|:..    ..:.|.|..|.|||:...||....||.|:|:||.:|.|
  Fly  1547 LLELDSPVQFDTHIVPICMPNDV----ADFTGRMATVTGWGRLKYGGGVPSVLQEVQVPIIENSV 1607

  Fly   419 CVQSYAKEKRYFSADQFDK---AVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSY 480
            |      ::.:.:|....|   :.||||..:|.||:|:|||||||:|..| .|  |:.|.|.||:
  Fly  1608 C------QEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRP-DG--RYELAGTVSH 1663

  Fly   481 GIGCARPNVPGVYSSTQYFMDWI 503
            ||.||.|.:||||..|.::..|:
  Fly  1664 GIKCAAPYLPGVYMRTTFYKPWL 1686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	7/51 (14%)
		Tryp_SPc	260..503	CDD:214473	101/251 (40%)
		Tryp_SPc	261..503	CDD:238113	101/250 (40%)
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	102/252 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010