DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and prss60.3

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	279	Identity:	94/279 - (33%)
Similarity:	131/279 - (46%)	Gaps:	48/279 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 LNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHC--- 306
            |||   ||. .....:||||..:..|:|||...| :....|..| |||:||::..|||||||
Zfish    24 LNV---CGQ-APLNTRIVGGVNASPGSWPWQVSL-HSPKYGGHF-CGGSLISSEWVLTAAHCLSG 82

  Fly   307 IRQDLQFVRLGEHDLSTDTETGHVDI-----NIARYVSHPDYNRRNGRSDMAILYLERNVEFTSK 366
            :.:....|.||..     |:.| ::|     |:|:...|..||.....:|:|:|.|...|.||:.
Zfish    83 VSETTLVVYLGRR-----TQQG-INIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNY 141

  Fly   367 IAPICLPHTANLRQKSY--VGYMPFVAGWGKTMEGGE--SAQVLNELQIPIYDNKVCVQSYAKEK 427
            |.|:||     ..|.|.  .|...::.|||....|..  :..:|.|..||:..|..|       .
Zfish   142 IRPVCL-----AAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRC-------N 194

  Fly   428 RYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLI----GVVSYGIGCARPN 488
            ....:......::|||:..|||||||||||||::        .|...:    |:.|:|.|||.||
Zfish   195 ALLGSGTVTNNMICAGLTQGGKDTCQGDSGGPMV--------TRLCTVWVQAGITSWGYGCADPN 251

  Fly   489 VPGVYSSTQYFMDWIIQQV 507
            .||||:....:..||..::
Zfish   252 SPGVYTRVSQYQSWISSKI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	87/258 (34%)
		Tryp_SPc	261..503	CDD:238113	87/257 (34%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	89/260 (34%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000