DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP005709

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_556350.3	Gene:	AgaP_AGAP005709 / 3290027	VectorBaseID:	AGAP005709	Length:	268	Species:	Anopheles gambiae

Alignment Length:	258	Identity:	76/258 - (29%)
Similarity:	112/258 - (43%)	Gaps:	42/258 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 KIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI--RQDLQFVRLGEHDLS 322
            :|.|||::...|.|:|..:.....|...| |.|.||:.|||||.|.|:  |..|. |.||..|::
Mosquito    29 RISGGELTDPRAVPFIVGILISGSSSHSF-CAGILISPRHVLTTASCVSNRPTLT-VLLGASDMT 91

  Fly   323 TDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLP---HTANLRQKSYV 384
            ...:.    |.:|..:.||:|:....|.|:|||.::|:......|....||   |..|    ::.
Mosquito    92 RIQQF----IGVANILIHPNYSSLFNRDDLAILTMDRDTPLNEYIQVANLPRWSHMGN----TFN 148

  Fly   385 GYMPFVAGWGKTMEGGESAQV-----LNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGV 444
            |:...::|||.|  |....:.     |..::.|:..|.||..|:     .|..|..    :|...
Mosquito   149 GFGTTISGWGNT--GNRDNEPIPTPNLQSIRTPVISNTVCGISH-----NFIRDDH----ICTSG 202

  Fly   445 LSGGKDTCQGDSGGPLMLPEPYQ----GQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
            ..||  .|.||.|||:.:.|..|    |...|:..|:    .||.|.. ..|:.....::.||
Mosquito   203 DIGG--PCNGDDGGPVTITEAGQPIVIGMHSFHYSGL----FGCDRGR-SAVHVRLSSYLSWI 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	74/256 (29%)
		Tryp_SPc	261..503	CDD:238113	74/255 (29%)
AgaP_AGAP005709	XP_556350.3	Tryp_SPc	29..258	CDD:214473	74/256 (29%)
AgaP_AGAP005709	XP_556350.3	Tryp_SPc	30..261	CDD:238113	76/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910