DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP004857

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_558259.2	Gene:	AgaP_AGAP004857 / 3289860	VectorBaseID:	AGAP004857	Length:	423	Species:	Anopheles gambiae

Alignment Length:	386	Identity:	89/386 - (23%)
Similarity:	154/386 - (39%)	Gaps:	116/386 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 CRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQ--VCCPTGQGITNTT 226
            |:..|.:.|:|...:.|.       ..|...|.        ::||: |.:  :||||..  |||.
Mosquito   102 CQLQDGRTGSCTPYRSCP-------KESVGTTI--------SICQH-GLEPIICCPTTP--TNTL 148

  Fly   227 PAPSQIV-----PKNTDEIPRRLLNVEEGCGSTVGYFKKI-------------VGGEVSRKGAWP 273
            ..|:::.     |.|........||      :.|.|:|:.             .|..|.|: .:|
Mosquito   149 SRPTRLSATGSRPTNPSSSSGYKLN------NCVSYWKQYKRTPTEEFEHIPSEGRPVGRE-EYP 206

  Fly   274 WIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI--RQDLQFVRLGEHDLSTDTETGHVDINIAR 336
            .||.:||...:..|  |.|.|::.::|||||.||  .:.|:.:.||....|::.:      .|..
Mosquito   207 HIAAIGYAQQNVWP--CTGVLVSDQYVLTAASCIASARGLKSIGLGFGIPSSNVQ------EIDE 263

  Fly   337 YVSHPDYNRRNGRSD---MAILYLERNVEFTSKIAPICL-PHTANLRQKSY-VGYMPFVAGWG-- 394
            .:.||.|.:  |..|   :|::.:...|:|:|.:.|.|| |.:..:..|.| :|     :|.|
Mosquito   264 IIIHPSYGK--GLKDANNVALVRMMNRVQFSSNVLPACLWPKSDKIPLKLYAIG-----SGTGGL 321

  Fly   395 --------------KTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVL 445
                          :::.||:::  :.:      |..||:::      |::.|     .:||.:.
Mosquito   322 RYVYPRSAMYNSDCRSLPGGDNS--ITD------DENVCIEN------YYATD-----TVCADLP 367

  Fly   446 SGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGC---ARPNVPGVYSSTQYFMDWI 503
            ....:.....||  :.:|         .::|..|..|||   ::.....|.|.....|:||
Mosquito   368 GNPVEGIVDQSG--IRIP---------LVVGTTSRTIGCLTSSKAQTVSVLSRIANHMNWI 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	10/53 (19%)
		Tryp_SPc	260..503	CDD:214473	62/281 (22%)
		Tryp_SPc	261..503	CDD:238113	62/280 (22%)
AgaP_AGAP004857	XP_558259.2	Tryp_SPc	197..418	CDD:304450	64/267 (24%)
AgaP_AGAP004857	XP_558259.2	Tryp_SPc	197..417	CDD:214473	62/265 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910