DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_796136.2	Gene:	Tmprss11g / 320454	MGIID:	2444058	Length:	417	Species:	Mus musculus

Alignment Length:	291	Identity:	91/291 - (31%)
Similarity:	139/291 - (47%)	Gaps:	41/291 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 SQIVPKNTDEIP----------RRLLNVEEGCGSTVGY--FKKIVGGEVSRKGAWPWIALLGYDD 282
            ||.:.|....:|          ..:||.:  |||.:.|  ..:|..|:.:.|.:|||.:.|..:
Mouse   145 SQSILKRDASLPYLREMNAAQAEHILNSD--CGSGMEYPPIARIADGKPADKASWPWQSSLQVE- 206

  Fly   283 PSGSPFKCGGTLITARHVLTAAHCI----RQDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDY 343
               ....||.:||.::.::|:|||.    ...|..|..| ..||:...|..|:    ..:.|.:|
Mouse   207 ---GIHLCGASLIGSQWLVTSAHCFDNYKNPKLWTVSFG-RTLSSPLTTRKVE----SIIVHENY 263

  Fly   344 NRRNGRSDMAILYLERNVEFTSKIAPICLPH-TANLRQKSYVGYMPFVAGWGKTMEGGESAQVLN 407
            .......|:|::.|...|.|:..:..:|||. |..:..||.|    ||.|||.....|.....|.
Mouse   264 ASHKHDDDIAVVKLSSPVLFSENLHRVCLPDATFQVLPKSKV----FVTGWGALKANGPFPNSLQ 324

  Fly   408 ELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRF 472
            |::|.|..|.||.|...    |..|  ....::|||.|:|..|.|:|||||||::.:   .:.::
Mouse   325 EVEIEIISNDVCNQVNV----YGGA--ISSGMICAGFLTGKLDACEGDSGGPLVISD---NRNKW 380

  Fly   473 YLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
            ||:|:||:||.|.:.|.||:|:...::.|||
Mouse   381 YLLGIVSWGIDCGKENKPGIYTRVTHYRDWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	79/247 (32%)
		Tryp_SPc	261..503	CDD:238113	79/246 (32%)
Tmprss11g	NP_796136.2	SEA	48..142	CDD:279699
		Tryp_SPc	185..411	CDD:214473	79/247 (32%)
		Tryp_SPc	186..414	CDD:238113	81/248 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910