DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Prss30

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_011244785.1	Gene:	Prss30 / 30943	MGIID:	1353645	Length:	347	Species:	Mus musculus

Alignment Length:	304	Identity:	100/304 - (32%)
Similarity:	147/304 - (48%)	Gaps:	49/304 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 TTPAPSQIVPKNT----------------DEIPRRLLNVEEGCGSTVGYFK---KIVGGEVSRKG 270
            :||.|..||...|                |.:|           |..|:.:   |||||:.:.:|
Mouse    30 STPHPQWIVDGLTLRRSYAGFFYNGWARGDILP-----------SVCGHSRDAGKIVGGQDALEG 83

  Fly   271 AWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQ----FVRLGEHDLSTDTETGHVD 331
            .|||...|...:..   ..|||:||....|||||||.|:.|.    .|::|...||. .|.....
Mouse    84 QWPWQVSLWITEDG---HICGGSLIHEVWVLTAAHCFRRSLNPSFYHVKVGGLTLSL-LEPHSTL 144

  Fly   332 INIARYVSHPDYNRRNGRS-DMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGK 395
            :.:.....||.|...:..| |:|::.|:..:. .|:..|:|||..   :.....|.:.:|.|||.
Mouse   145 VAVRNIFVHPTYLWADASSGDIALVQLDTPLR-PSQFTPVCLPAA---QTPLTPGTVCWVTGWGA 205

  Fly   396 TMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKA-VLCAGVLSGGKDTCQGDSGGP 459
            |.| .:.|.||.||.:|:.|::.|.:.|..:....|.::..:: :||||.:.|.||:||||||||
Mouse   206 TQE-RDMASVLQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLCAGYVEGQKDSCQGDSGGP 269

  Fly   460 LMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
            |:.    .....:..:|:.|:|||||||..||||:....::|||
Mouse   270 LVC----SINSSWTQVGITSWGIGCARPYRPGVYTRVPTYVDWI 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	88/248 (35%)
		Tryp_SPc	261..503	CDD:238113	87/247 (35%)
Prss30	XP_011244785.1	Tryp_SPc	74..312	CDD:238113	89/249 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910