Protein Alignment CG1299 and F2

DIOPT Version :9

• Sequence 1: NP_647862.1
• Gene: CG1299 / 38496
• FlyBaseID: FBgn0035501
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_075213.2
• Gene: F2 / 29251
• RGDID: 61996
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 150/608 - (24%)
• Similarity: 219/608 - (36%)
• Gaps: 173/608 - (28%)

  Fly    29 QRRQVRQNCITPENYYGSCVALTYCPQVVNIFQT------TSRDRAQRYVIALQRSC-------- 79
            ::..:.:.|:..:..|.........||..::|..      :.|...:.::..|:..|
  Rat    53 RKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGLNY 117

  Fly    80 -GTRSINGDPVICCT-------EPRYNPVTERP---------RNPFFPSESTFIGP---QPPPEV 124
             |..|:....:.|..       .|..|..| .|         |||    :|:..||   ...|.|
  Rat   118 HGNVSVTHTGIECQLWRSRYPHRPDINSTT-HPGADLKENFCRNP----DSSTSGPWCYTTDPTV 177

  Fly   125 PDNPFLIP------------TPRTTTTTTTTTPAPIPD----------------TSAAPLIE--- 158
            ......||            |||:..:....:| |:.:                |..:|.:.
  Rat   178 RREECSIPVCGQEGRTTVKMTPRSRGSKENLSP-PLGECLLERGRLYQGNLAVTTLGSPCLAWDS 241

  Fly   159 -PRGTV----------------CRGPD-----------TKPG-NCVEIKECASLLNE-------- 186
             |..|:                ||.||           .:|| ....:..|...:.|
  Rat   242 LPTKTLSKYQNFDPEVKLVQNFCRNPDRDEEGAWCFVAQQPGFEYCSLNYCDEAVGEENHDGDES 306

  Fly   187 LRSRSQDATFANFLRASNAVCQNKGTQVCCPTGQGITNTTPAPSQIVPKNTDEIPRRLLNVEEGC 251
            :..|:.||.|..|.....             .|.|..:....|.......||:..:.||:
  Rat   307 IAGRTTDAEFHTFFDERT-------------FGLGEADCGLRPLFEKKSLTDKTEKELLD----- 353

  Fly   252 GSTVGYFK-KIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI-------- 307
                .|.. :||.|..:.||..||..:|....|  ....||.:||:.|.||||||||
  Rat   354 ----SYIDGRIVEGWDAEKGIAPWQVMLFRKSP--QELLCGASLISDRWVLTAAHCILYPPWDKN 412

  Fly   308 --RQDLQFVRLGEHDLSTDTETGHVDINIAR--YVSHPDYN-RRNGRSDMAILYLERNVEFTSKI 367
              ..|| .||:|:|. .|..|.....|::..  |: ||.|| |.|...|:|:|.|::.|.|:..|
  Rat   413 FTENDL-LVRIGKHS-RTRYERNVEKISMLEKIYI-HPRYNWRENLDRDIALLKLKKPVPFSDYI 474

  Fly   368 APICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQ--------IPIYDNKVCVQSYA 424
            .|:|||....:......||...|.|||...|...:.  :||:|        :||.:..||..|
  Rat   475 HPVCLPDKQTVTSLLQAGYKGRVTGWGNLRETWTTN--INEIQPSVLQVVNLPIVERPVCKAS-- 535

  Fly   425 KEKRYFSADQFDKAVLCAGV-LSGGK--DTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCAR 486
              .|....|.    :.|||. ::..|  |.|:||||||.::..||..  |:|.:|:||:|.||.|
  Rat   536 --TRIRITDN----MFCAGFKVNDTKRGDACEGDSGGPFVMKSPYNH--RWYQMGIVSWGEGCDR 592

  Fly   487 PNVPGVYSSTQYFMDWIIQQVQD 509
            ....|.|:.......| :|:|.|
  Rat   593 NGKYGFYTHVFRLKRW-MQKVID 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829	11/70 (16%)
		CLIP	164..216	CDD:288855	13/71 (18%)
		Tryp_SPc	260..503	CDD:214473	91/266 (34%)
		Tryp_SPc	261..503	CDD:238113	91/265 (34%)
F2	NP_075213.2	GLA	25..89	CDD:214503	5/35 (14%)
		KR	107..189	CDD:214527	18/86 (21%)
		Kringle	215..292	CDD:278480	10/76 (13%)
		Thrombin_light	312..359	CDD:286482	12/68 (18%)
		Tryp_SPc	359..608	CDD:214473	91/265 (34%)
		Tryp_SPc	360..612	CDD:238113	93/269 (35%)
		High affinity receptor-binding region which is also known as the TP508 peptide	547..569		11/21 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910