DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and F10

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	423	Identity:	120/423 - (28%)
Similarity:	181/423 - (42%)	Gaps:	106/423 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 GTVCR-GPDTKPGNC--------------VEIKECASLLNELRS-----------RSQDATFAN- 198
            |..|. .|....|.|              .|.|.|...:.:|.|           ..|::...:
  Rat    87 GDQCESSPCQNQGECRDGLGSYTCTCTEGFEGKNCELFVRKLCSLDNGDCDQFCREEQNSVVCSC 151

  Fly   199 ----FLRASNAVCQNKGTQVCCPTGQG---------ITNTTPAPSQIVPKNTD-----EIPRRLL 245
                ||......|.:.....|..|.:|         .:|:.|.|..::| :.|     |.|..||
  Rat   152 AKGYFLGNDGKSCLSTAPFPCGKTNKGRAKRSVALNTSNSEPDPEDLMP-DADILYPTESPSELL 215

  Fly   246 NV-----EEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAH 305
            |:     |......:    :||||:..::|..||.||| :.|.....| ||||::...::|||||
  Rat   216 NLNKTEPEANSDDVI----RIVGGQECKRGECPWQALL-FSDEETDGF-CGGTILNEFYILTAAH 274

  Fly   306 CIRQDLQF-VRLGEHDLSTDTETG-----HVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFT 364
            |:.|..:| ||:|  ||:|:.|.|     .||:    .:.|..:.|.....|:|:|.|:..:.|.
  Rat   275 CLHQAKRFKVRVG--DLNTEQEDGGEMVHEVDM----IIKHNKFQRDTYDFDIAMLRLKTPITFR 333

  Fly   365 SKIAPICLP-----HTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYA 424
            ..:||.|||     ....:.||:.:     |:|:|:|.|.|..::||..:::|..|...|..|.:
  Rat   334 ENVAPACLPQKDWAEATLMTQKTGI-----VSGFGRTHEKGRQSKVLKMMEVPYVDRNTCRLSTS 393

  Fly   425 KEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRF----YLIGVVSYGIGCA 485
                 ||..|   .:.|||..:..:|.||||||||.:        .||    ::.|:||:|.|||
  Rat   394 -----FSITQ---NMFCAGYDAKQEDACQGDSGGPHV--------TRFKDTYFVTGIVSWGEGCA 442

  Fly   486 RPNVPGVYSSTQYFMDWI-------IQQVQDTP 511
            |....|:|:....|:.||       :....:||
  Rat   443 RKGKYGIYTKVTAFLKWIDRSMKARVGPTSETP 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	13/82 (16%)
		Tryp_SPc	260..503	CDD:214473	88/257 (34%)
		Tryp_SPc	261..503	CDD:238113	88/256 (34%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011	7/34 (21%)
		FXa_inhibition	129..164	CDD:405372	4/34 (12%)
		Tryp_SPc	232..462	CDD:238113	90/258 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920