DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and TPSD1

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_036349.1	Gene:	TPSD1 / 23430	HGNCID:	14118	Length:	242	Species:	Homo sapiens

Alignment Length:	212	Identity:	69/212 - (32%)
Similarity:	104/212 - (49%)	Gaps:	24/212 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 IVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQ-----FVRLGEHD 320
            ||||:.:.:..|||...|....|....| |||:||..:.|||||||:..|::     .|:|.|..
Human    38 IVGGQEAPRSKWPWQVSLRVRGPYWMHF-CGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQH 101

  Fly   321 LSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVG 385
            |....:.    :.::|.:.||.:......:|:|:|.||..|..:|.|..:.||..:    :::..
Human   102 LYYQDQL----LPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPAS----ETFPP 158

  Fly   386 YMP-FVAGWGKTMEGGE--SAQVLNELQIPIYDNKVCVQSY---AKEKRYFSADQFDKAVLCAGV 444
            .|| :|.|||.......  ....|.|:::|:.:|.:|...|   ......|...:.|  :||||
Human   159 GMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDD--MLCAG- 220

  Fly   445 LSGGKDTCQGDSGGPLM 461
             |...|:|||||||||:
Human   221 -SENHDSCQGDSGGPLV 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	69/212 (33%)
		Tryp_SPc	261..503	CDD:238113	69/212 (33%)
TPSD1	NP_036349.1	Tryp_SPc	38..242	CDD:238113	69/212 (33%)
TPSD1	NP_036349.1	Tryp_SPc	38..240	CDD:214473	69/212 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910