DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and F9

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	285	Identity:	90/285 - (31%)
Similarity:	148/285 - (51%)	Gaps:	36/285 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 NTDEIPRRLLNVEEGCGSTVGY--FKKIVGGEVSRKGAWPW-IALLGYDDPSGSPFKCGGTLITA 297
            |:.|....|.|:.:   ||..:  |.::||||.::.|.:|| :.|.|..|..     |||:::..
Human   203 NSTEAETILDNITQ---STQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAF-----CGGSIVNE 259

  Fly   298 RHVLTAAHCIRQDLQF-VRLGEHDLSTDTETGHVD--INIARYVSHPDYNRRNGR--SDMAILYL 357
            :.::|||||:...::. |..|||::.   ||.|.:  .|:.|.:.|.:||....:  .|:|:|.|
Human   260 KWIVTAAHCVETGVKITVVAGEHNIE---ETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLEL 321

  Fly   358 ERNVEFTSKIAPICL--PHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCV 420
            :..:...|.:.|||:  ....|:..|...||   |:|||:....|.||.||..|::|:.|...|:
Human   322 DEPLVLNSYVTPICIADKEYTNIFLKFGSGY---VSGWGRVFHKGRSALVLQYLRVPLVDRATCL 383

  Fly   421 QSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCA 485
            :| .|...|       ..:.|||...||:|:||||||||.:.    :.:...:|.|::|:|..||
Human   384 RS-TKFTIY-------NNMFCAGFHEGGRDSCQGDSGGPHVT----EVEGTSFLTGIISWGEECA 436

  Fly   486 RPNVPGVYSSTQYFMDWIIQQVQDT 510
            .....|:|:....:::||.::.:.|
Human   437 MKGKYGIYTKVSRYVNWIKEKTKLT 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	80/250 (32%)
		Tryp_SPc	261..503	CDD:238113	80/249 (32%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	82/252 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910