DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Proc

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_006525784.1	Gene:	Proc / 19123	MGIID:	97771	Length:	484	Species:	Mus musculus

Alignment Length:	391	Identity:	110/391 - (28%)
Similarity:	175/391 - (44%)	Gaps:	72/391 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 DTSAAPLIEPRGTVCRGPDTKPGNCV--------------EIKECASLLNELRSRSQDATFANFL 200
            |..:||   |....|..|....|.|:              |.|.|...|     |.||.
Mouse   113 DQCSAP---PLDHQCDSPCCGHGTCIDGIGSFSCSCDKGWEGKFCQQEL-----RFQDC------ 163

  Fly   201 RASNAVC------QNKGTQVCCPTGQGITNTTPAPSQIVPKNTDEIP-----------RRLLNVE 248
            |.:|..|      ::.|.:..|..|..:     |...:..|:|...|           |::|..:
Mouse   164 RVNNGGCLHYCLEESNGRRCACAPGYEL-----ADDHMRCKSTVNFPCGKLGRWIEKKRKILKRD 223

  Fly   249 EGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQF 313
            ......:....:||.|.::::|..||.|:| .|  |.....|||.||....|||||||:....:.
Mouse   224 TDLEDELEPDPRIVNGTLTKQGDSPWQAIL-LD--SKKKLACGGVLIHTSWVLTAAHCVEGTKKL 285

  Fly   314 -VRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTAN 377
             |||||:||.. .:...:|::|...:.||:|.|.:..:|:|:|.|.:....:..|.|||||:...
Mouse   286 TVRLGEYDLRR-RDHWELDLDIKEILVHPNYTRSSSDNDIALLRLAQPATLSKTIVPICLPNNGL 349

  Fly   378 LRQKSYVGYMPFVAGWG----KTMEGGESAQ-VLNELQIPIYDNKVCVQSYAKEKRYFSADQFDK 437
            .::.:..|....|.|||    :..:|..:.. :|..::||:.....||:..   |...|.:
Mouse   350 AQELTQAGQETVVTGWGYQSDRIKDGRRNRTFILTFIRIPLVARNECVEVM---KNVVSEN---- 407

  Fly   438 AVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDW 502
             :||||::...:|.|.||||||:::  .::|  .::|:|:||:|.||...|..|:|:....::.|
Mouse   408 -MLCAGIIGDTRDACDGDSGGPMVV--FFRG--TWFLVGLVSWGEGCGHTNNYGIYTKVGSYLKW 467

  Fly   503 I 503
            |
Mouse   468 I 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	15/71 (21%)
		Tryp_SPc	260..503	CDD:214473	81/248 (33%)
		Tryp_SPc	261..503	CDD:238113	81/247 (33%)
Proc	XP_006525784.1	GLA	50..110	CDD:214503
		EGF_CA	111..155	CDD:238011	10/44 (23%)
		FXa_inhibition	163..198	CDD:373209	7/45 (16%)
		Tryp_SPc	236..470	CDD:238113	83/249 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910