DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and F25E5.4

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001379698.1	Gene:	F25E5.4 / 179133	WormBaseID:	WBGene00017785	Length:	425	Species:	Caenorhabditis elegans

Alignment Length:	340	Identity:	70/340 - (20%)
Similarity:	114/340 - (33%)	Gaps:	108/340 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 DEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPW---IALLGYDDPSGSPFKCGGTLITARH 299
            ||....:|.::  || ..|..::.:.|:.:|.|..||   :.:..........|...||||:|||
Worm    21 DEKHNEILQLK--CG-IKGSQREFINGDTARPGDHPWAVSVYVKANTTSKNGVFLGPGTLISARH 82

  Fly   300 VLTAAHCIRQDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDY---------NRRNGRSDMAIL 355
            |||.......|.:...||:.:::......|.::: ...:.|.||         ::|:.::.:|.:
Worm    83 VLTFNSIKVVDGKRRILGQEEVNGACNGNHFELS-QDEMYHFDYDFEHFKNFDSKRDFKNTIASV 146

  Fly   356 YLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNK--- 417
            |:....:.:        |..|.|                          ::.||:.....||
Worm   147 YIINGCQSS--------PPPATL--------------------------LMFELKESALHNKKGY 177

  Fly   418 -VCVQSYAKEKRYFSADQFDKAVL-----------------------CAGVLSGGKDTCQGDSGG 458
             ||:.:..|   :|.|..|:...|                       ||..:...:..|.||.||
Worm   178 PVCISNSPK---HFDASDFEVFGLNQQGRLVSGAFAPTNCTATAPFSCAHAVKQNQGLCSGDFGG 239

  Fly   459 P---------LML-------------PEPYQGQLRFYLIGVVSYGI----GCARPNVPGVYSSTQ 497
            .         .||             ||..:. .:|..||.....|    |...|:.|....||.
Worm   240 SAVSRIDNRFTMLGFFAQGNKNCKAKPETLEA-FKFLNIGYYREEICEVTGICTPSPPSPEESTT 303

  Fly   498 YFMDWIIQ-QVQDTP 511
            .....:|. :..|||
Worm   304 LSPSELIPGESTDTP 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	60/307 (20%)
		Tryp_SPc	261..503	CDD:238113	60/306 (20%)
F25E5.4	NP_001379698.1	DUF316	5..291	CDD:367641	62/311 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910