DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and try-1

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_494910.2	Gene:	try-1 / 173856	WormBaseID:	WBGene00006619	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	254	Identity:	89/254 - (35%)
Similarity:	123/254 - (48%)	Gaps:	36/254 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 KIVGGEVSRKGAWPW----IALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQ----FVRL 316
            :::||..|...:|||    ::.||:       .:|||:||....|||||||..:|.:    .||:
Worm    57 RLIGGSESSPHSWPWTVQLLSRLGH-------HRCGGSLIDPNFVLTAAHCFAKDRRPTSYSVRV 114

  Fly   317 GEHDLSTDTETGHVDINIARYVSHPDYNRRNGRS-DMAILYLERNVEFTSKIAPICLPHTANLRQ 380
            |.|...:.:......::|     ||.||.....| |.||:.:...|..::...|||||....:..
Worm   115 GGHRSGSGSPHRVTAVSI-----HPWYNIGFPSSYDFAIMRIHPPVNTSTTARPICLPSLPAVEN 174

  Fly   381 KSYVGYMPFVAGWGKTMEGGE-SAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGV 444
            :..|     |.|||.|:||.. ||..|.|:.:|:.....|    :....|...... .::||||.
Worm   175 RLCV-----VTGWGSTIEGSSLSAPTLREIHVPLLSTLFC----SSLPNYIGRIHL-PSMLCAGY 229

  Fly   445 LSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
            ..|..|:||||||||||.......:    |.||||:|||||||.:||||.:......||
Worm   230 SYGKIDSCQGDSGGPLMCARDGHWE----LTGVVSWGIGCARPGMPGVYGNVHSASTWI 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	87/252 (35%)
		Tryp_SPc	261..503	CDD:238113	87/251 (35%)
try-1	NP_494910.2	Tryp_SPc	59..285	CDD:238113	89/252 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910