DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Mcpt2

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_032597.1	Gene:	Mcpt2 / 17225	MGIID:	96938	Length:	244	Species:	Mus musculus

Alignment Length:	260	Identity:	72/260 - (27%)
Similarity:	126/260 - (48%)	Gaps:	33/260 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 LNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQ 309
            |.:..|.|:     ::|:||..::..:.|::|.|.:...:||..:|||.||..:.|:|||||...
Mouse    10 LLLPSGAGA-----EEIIGGVEAKPHSRPYMAYLKFTTKNGSKERCGGFLIAPQFVMTAAHCNGS 69

  Fly   310 DLQFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPH 374
            ::..: ||.|:::.:..|..: |...:...||.:...:|..|:.:|.|::..|..|.:..|.||.
Mouse    70 EISVI-LGAHNINKNEPTQQI-IKTEKTFVHPKFQYLSGFYDIMLLKLQKKAELNSDVDVISLPS 132

  Fly   375 TANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAV 439
            :::..:.   |.|.:.||||||.:....:..|.|:::.|.|.:.|..         .:|...:..
Mouse   133 SSDFIKP---GKMCWTAGWGKTGKNNPLSVTLREVELRIMDQEACKD---------HSDYDYQLQ 185

  Fly   440 LCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCA-RPNVPGVYSSTQYFMDWI 503
            :|||..:..|...||||||||:...             |::||..: ....|.|::...|::.||
Mouse   186 VCAGSPTTSKSIGQGDSGGPLVCDS-------------VAHGIASSYEAKAPAVFTRISYYLPWI 237

Fly 504 503
Mouse 238 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	67/243 (28%)
		Tryp_SPc	261..503	CDD:238113	67/242 (28%)
Mcpt2	NP_032597.1	Tryp_SPc	20..237	CDD:214473	67/243 (28%)
Mcpt2	NP_032597.1	Tryp_SPc	21..240	CDD:238113	69/244 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910