DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP011427

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_317876.4	Gene:	AgaP_AGAP011427 / 1278263	VectorBaseID:	AGAP011427	Length:	868	Species:	Anopheles gambiae

Alignment Length:	267	Identity:	90/267 - (33%)
Similarity:	132/267 - (49%)	Gaps:	27/267 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 TVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGS--PFKCGGTLITARHVLTAAHC------IRQD 310
            ||.|     ||..:.||.:..:|.:|: ..||:  .:.|||:|||.|.||||:||      :..|
Mosquito   302 TVAY-----GGVRAYKGEFQHMAAIGW-TRSGATIDYLCGGSLITWRFVLTASHCSVDSNNLPPD 360

  Fly   311 LQFVRLGEHDL-STDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPH 374
            .  ||||:.|| |||.:.....|.|||::.||.|.......|:|::.||:||...|.|...|:
Mosquito   361 T--VRLGDTDLASTDDDESAQQIPIARFIKHPQYRESRRYYDIAVVELEKNVIPNSAICVACV-- 421

  Fly   375 TANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAV 439
               .|:......:....|:|....|.|.:..|.::|:...|..:|.:.....:|.......|..
Mosquito   422 ---WREPEAPEDLIDAVGFGALGFGKELSSTLQKVQLHALDATICAERIPTNRRQMPEGLRDDQ- 482

  Fly   440 LCAGVLSGGKDTCQGDSGGPLM-LPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
            |||  .|...|||:|||||||. |.....|.:..:::||||:|..|...:. |||:....::|||
Mosquito   483 LCA--RSETMDTCEGDSGGPLQTLRYDLLGNIFSFIVGVVSFGTPCVEGST-GVYTRVSSYLDWI 544

  Fly   504 IQQVQDT 510
            .::|..:
Mosquito   545 EKEVNQS 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	84/252 (33%)
		Tryp_SPc	261..503	CDD:238113	84/251 (33%)
AgaP_AGAP011427	XP_317876.4	Tryp_SPc	21..261	CDD:238113
		Tryp_SPc	21..259	CDD:214473
		Tryp_SPc	306..546	CDD:238113	86/251 (34%)
		Tryp_SPc	306..544	CDD:214473	84/249 (34%)
		Tryp_SPc	625..862	CDD:214473
		Tryp_SPc	630..864	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910