DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and CLIPD2

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_317284.4	Gene:	CLIPD2 / 1277787	VectorBaseID:	AGAP008183	Length:	512	Species:	Anopheles gambiae

Alignment Length:	575	Identity:	162/575 - (28%)
Similarity:	239/575 - (41%)	Gaps:	130/575 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKSMCCVSAVITLL-------PLVLLPPPTVAQFNQRRQVRQN-----------------CITPE 41
            |||: ||....|::       .....|||     .|.|||..|                 |:|.:
Mosquito     1 MKSV-CVRLCDTMVKRCGQSASKTAQPPP-----RQPRQVWLNAHVPHADWKQTLGDGSPCLTAK 59

  Fly    42 NYYGSCVALTYCPQVVNIFQTTSRDRAQRYVIALQRSCGTRSINGDPV--ICCTEPRYNPVTERP 104
            .:.|.|.:...|   ...|:.......:.:|:....:|...:..|...  :|||    ||:|..|
Mosquito    60 GHLGFCTSFRKC---YPYFKVPDLSVWESWVLGNYDTCSYFNEQGRQAFGVCCT----NPITPLP 117

  Fly   105 --RNPFF---------PSESTFIGPQP--PPEVPDN----PFLIPTPRTTTTTTTTTPA----PI 148
              .||..         |..||.:|.:|  ||...:|    |..|||.....|..|..||    |.
Mosquito   118 IDSNPVIEAAPGVMLPPPASTGLGSEPNKPPNKNNNYPSWPPPIPTHPPDHTPATHPPAFGGPPA 182

  Fly   149 PDTSAAPLIEPRGTVCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQ 213
            | |:.:.:::|..:   .|..:|                     ..|:....|......|.....
Mosquito   183 P-TTVSSVVDPAAS---EPTQRP---------------------TTTWPTRPRPPQVPNQPTPAP 222

  Fly   214 VCCPTG-----------QGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGY--FKKIVGGE 265
            ...|.|           ..|:...|:.|.:|..:...:         |||...|.  .::||||.
Mosquito   223 PAQPIGVWPPPVPTHPPLEISTLPPSSSGVVVSDPSNL---------GCGVKNGNPDTERIVGGH 278

  Fly   266 VSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQF------VRLGEHDLSTD 324
            .:....|||||.|   ..:|..| |||:||.:.|:||||||:.....:      |:||:|::.::
Mosquito   279 NADPNEWPWIAGL---FNNGRQF-CGGSLIDSIHILTAAHCVAHMSSYDVARLSVKLGDHNIRSN 339

  Fly   325 TETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPF 389
            ||..||:..:.|.|.|..::.|...:|:|:|.:::.|.||.::.|||||...:.|  :|.|....
Mosquito   340 TEVQHVERRVKRLVRHRGFDSRTLYNDVAVLTMDQAVPFTKQVRPICLPAADSTR--AYSGLTAT 402

  Fly   390 VAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQG 454
            |.|||...|.|....:|.|:.:||:.|..|...|.........|    .:||||  ...||:|.|
Mosquito   403 VIGWGSLRENGPQPAILQEVNLPIWTNNECRIKYGPAAPGGIID----TMLCAG--QAAKDSCSG 461

  Fly   455 DSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQD 509
            |||||||:.:.     ::..:||||:||||.:...||||:....|:.||.:.:.|
Mosquito   462 DSGGPLMVNDG-----KWTQVGVVSWGIGCGKGQYPGVYTRVTAFLPWIKKNIND 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829	10/57 (18%)
		CLIP	164..216	CDD:288855	5/51 (10%)
		Tryp_SPc	260..503	CDD:214473	92/248 (37%)
		Tryp_SPc	261..503	CDD:238113	92/247 (37%)
CLIPD2	XP_317284.4	Tryp_SPc	273..505	CDD:214473	92/248 (37%)
CLIPD2	XP_317284.4	Tryp_SPc	274..508	CDD:238113	94/250 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910