DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and SCRASP2

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_316661.5	Gene:	SCRASP2 / 1277217	VectorBaseID:	AGAP006631	Length:	1343	Species:	Anopheles gambiae

Alignment Length:	286	Identity:	95/286 - (33%)
Similarity:	136/286 - (47%)	Gaps:	45/286 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 CGSTVG--YF---KKIVGGEVSRKGAWPWIALLGYDDPSGSP---FKCGGTLITARHVLTAAHCI 307
            ||....  ||   |:||||..|..|.||:||.:     .|.|   |.|.|.||..:.||||:|||
Mosquito  1065 CGKVRNRKYFKATKRIVGGSTSNPGDWPFIAAI-----LGGPEEVFYCAGVLIADQWVLTASHCI 1124

  Fly   308 RQDLQ----------FVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGR-SDMAILYLERNV 361
            .....          .::||.....:.|..|. .:.:...:.||.||..... :|:|:..|...|
Mosquito  1125 GNSPTSHTMRNVNDWTIQLGITRRRSHTYYGQ-KVKVKTVIPHPMYNLHIPHDNDIALFQLATRV 1188

  Fly   362 EFTSKIAPICL--PHTANLRQKSYVGYMPFVAGWGK------TMEGGESAQVLNELQIPIYDNKV 418
            .|...:.|:||  ||...|.    .|....|.||||      |..|......|||:.:||...::
Mosquito  1189 AFHEHLLPVCLPPPHIRELP----TGINCTVVGWGKREERNSTPNGASYEPTLNEVNVPIVSREL 1249

  Fly   419 CVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIG 483
            |:.       :.......:.::|||...||:|.|||||||||:.|.|.:.. |:::.|:||:|:.
Mosquito  1250 CID-------WLETFNVTEGMICAGYQEGGRDACQGDSGGPLLCPYPNEKD-RWFVGGIVSWGVR 1306

  Fly   484 CARPNVPGVYSSTQYFMDWIIQQVQD 509
            ||.|.:||||::...|:.||:.|:.:
Mosquito  1307 CAHPKLPGVYANVPKFIPWILAQINN 1332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	87/264 (33%)
		Tryp_SPc	261..503	CDD:238113	87/263 (33%)
SCRASP2	XP_316661.5	Fz	753..857	CDD:279700
		LDLa	889..918	CDD:238060
		LDLa	921..955	CDD:294076
		SRCR_2	956..>1011	CDD:295335
		Tryp_SPc	1079..1326	CDD:214473	87/264 (33%)
		Tryp_SPc	1080..1326	CDD:238113	87/263 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910