DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP006385

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_316419.4	Gene:	AgaP_AGAP006385 / 1276997	VectorBaseID:	AGAP006385	Length:	260	Species:	Anopheles gambiae

Alignment Length:	248	Identity:	78/248 - (31%)
Similarity:	122/248 - (49%)	Gaps:	24/248 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 KIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI--RQDLQFVRLGEHDLS 322
            ::|.||.::.|.:|:...|.....:|....|||:|:....||||.||:  .:.:: |.||..|.|
Mosquito    27 RVVNGETAKLGQFPYQVRLTLHVGNGQQALCGGSLLNEEWVLTAGHCVMLAKSVE-VHLGAVDFS 90

  Fly   323 TDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYM 387
            .:|..|.:.:....:..|..||.....:|:|::.|...|||:.::.|:.||    ...:.:.|..
Mosquito    91 DNTNDGRLVLESTEFFKHEKYNPLFVANDVALVKLPSKVEFSERVQPVRLP----TGDEDFAGRE 151

  Fly   388 PFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTC 452
            ..|:|||..:.||:.||.|....:.:..||.|       ::.||.....|:.||| |....:..|
Mosquito   152 VVVSGWGLMVNGGQVAQELQYATLKVIPNKQC-------QKTFSPLLVRKSTLCA-VGEELRSPC 208

  Fly   453 QGDSGGPLMLPEPYQGQLRFYLIGVVSYG--IGCARPNVPGVYSSTQYFMDWI 503
            .|||||||:|.|...      |:||||:|  .||.:.: |..::....|.||:
Mosquito   209 NGDSGGPLVLAEDKT------LVGVVSFGHAQGCDKGH-PAAFARVTAFRDWV 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	77/246 (31%)
		Tryp_SPc	261..503	CDD:238113	77/245 (31%)
AgaP_AGAP006385	XP_316419.4	Tryp_SPc	27..254	CDD:214473	77/246 (31%)
AgaP_AGAP006385	XP_316419.4	Tryp_SPc	28..257	CDD:238113	78/247 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910