DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP006192

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_316257.4	Gene:	AgaP_AGAP006192 / 1276857	VectorBaseID:	AGAP006192	Length:	346	Species:	Anopheles gambiae

Alignment Length:	277	Identity:	79/277 - (28%)
Similarity:	127/277 - (45%)	Gaps:	39/277 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 CGSTVGYFKK--IVGGEVSRKGAWPW-IALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQ 312
            ||. |...|:  |.||..|..|.||| :|:...:....:.:|||||:|....||||.||:.::.:
Mosquito    26 CGQ-VQVLKQGLIFGGTASTPGMWPWHVAVFHRESIRRTSYKCGGTIINRDTVLTAYHCVVENQR 89

  Fly   313 -------FVRLGEHDLSTDTETGHVDIN-IARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAP 369
                   ..|.|..||.....|  |..| :...:|.|..:.|....|:|||.::....:...:.|
Mosquito    90 PIAAGRLVARAGLFDLDVGGPT--VQENRVFDVISPPGASARTFDDDIAILKMQTQFTYDDYVQP 152

  Fly   370 ICLPHTANLRQK--SYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSA 432
            :|:   .::||.  ..||....|.|||.|.:...||: |.:..:|:...:.|:   |.::..||.
Mosquito   153 VCI---RSVRQDIGQLVGAYGTVVGWGWTEQSTTSAE-LRQANVPVVSAEDCL---ASDRNLFSQ 210

  Fly   433 DQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGV----- 492
            ....| |.||| ...|..:|.|||||.:.    ::....::|.|:.|:....|:.:  |:
Mosquito   211 VLTTK-VYCAG-SRNGTSSCNGDSGGGMF----FRMSGYWFLRGLTSFSAVDAKQS--GICDSHG 267

  Fly   493 ---YSSTQYFMDWIIQQ 506
               |:....::||:.:|
Mosquito   268 YVGYTDVAKYLDWLREQ 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	73/263 (28%)
		Tryp_SPc	261..503	CDD:238113	73/260 (28%)
AgaP_AGAP006192	XP_316257.4	Tryp_SPc	37..284	CDD:238113	74/263 (28%)
AgaP_AGAP006192	XP_316257.4	Tryp_SPc	37..280	CDD:214473	72/259 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910