DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP005704

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_315712.4	Gene:	AgaP_AGAP005704 / 1276373	VectorBaseID:	AGAP005704	Length:	305	Species:	Anopheles gambiae

Alignment Length:	261	Identity:	75/261 - (28%)
Similarity:	115/261 - (44%)	Gaps:	47/261 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 KKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQFVRLGEHDLST 323
            ::|:.|....:|..|:.|.:...:...:.| |||.|::...|||||.|:.        |:.|||.
Mosquito    60 QRILNGVTVARGDIPYAAAILISEEFATYF-CGGVLVSELFVLTAASCVE--------GDRDLSI 115

  Fly   324 DTETGHVDIN-------IARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQK 381
            ........||       ::..:.||    ....:|:|:|.|.|.|.....|.|:.||   |.||:
Mosquito   116 TVLLDAAQINTAGEFIAVSEIIVHP----APSDNDIALLRLNRAVRLNDNIRPVTLP---NRRQR 173

  Fly   382 --SYVGYMPFVAGWGKTMEGGESAQVLNELQI---PIYDNKVCVQSYAKEKRYFSADQFDKAVLC 441
              ::|..:..::|||:|......|..||.|::   .:..|..|..|:.    :...||.    :|
Mosquito   174 TMTFVNQLASISGWGRTASNTNEALPLNNLRLVRNHVMSNFNCGVSFP----FTITDQH----IC 230

  Fly   442 AGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSY----GIGCARPNVPGVYSSTQYFMDW 502
            ....||  ..|.||.||||...:...|  |.:|||:.|:    |.|..||.   |::....::||
Mosquito   231 ITGDSG--SACAGDEGGPLTTVDVVTG--RTFLIGLYSFTSFLGCGMGRPT---VHTRITEYLDW 288

  Fly   503 I 503
            |
Mosquito   289 I 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	73/258 (28%)
		Tryp_SPc	261..503	CDD:238113	73/257 (28%)
AgaP_AGAP005704	XP_315712.4	Tryp_SPc	61..289	CDD:214473	73/258 (28%)
AgaP_AGAP005704	XP_315712.4	Tryp_SPc	62..292	CDD:238113	75/259 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910