DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP008649

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_314746.4	Gene:	AgaP_AGAP008649 / 1275498	VectorBaseID:	AGAP008649	Length:	312	Species:	Anopheles gambiae

Alignment Length:	292	Identity:	103/292 - (35%)
Similarity:	144/292 - (49%)	Gaps:	49/292 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 NTTPAPSQI--------VPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGY 280
            |.||..|.|        ||  ...:|..|               :::||..|....:||:|.|.|
Mosquito    33 NPTPILSSISRSVVCGKVP--NPPLPNSL---------------RVIGGNTSDIDQYPWMAALYY 80

  Fly   281 DDPSGSPFKCGGTLITARHVLTAAHCI-RQDLQ--FVRLGEHDLST-DTETGHVDINIARYVSHP 341
                ...|.|||:||..|::||||||: |.|..  .|.|...::.| :.|..|  ..:||.|.:
Mosquito    81 ----RQQFTCGGSLINDRYILTAAHCVARMDAAGFEVYLRRPNIVTLNPEAVH--RRVARIVMN- 138

  Fly   342 DYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVL 406
            .|......:|:|:|.|:..|.....:.|||||    :...::.|....|.||| |.|.||.::.|
Mosquito   139 RYQELRNNNDVALLLLKEPVGVADGLVPICLP----VDGSNFDGKEAIVTGWG-TTESGELSEHL 198

  Fly   407 NELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLR 471
            .:|.:||..|:.|     ::..||.. |....:||||.|.||:|:|||||||||.|.:....|.:
Mosquito   199 QQLTVPILTNQQC-----RKSGYFRF-QITAKMLCAGYLEGGRDSCQGDSGGPLQLAKGETDQQQ 257

  Fly   472 FYLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
              ::||||:|..||:.|.||||:....|:.||
Mosquito   258 --IVGVVSWGNECAQRNYPGVYARVTRFVSWI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	92/246 (37%)
		Tryp_SPc	261..503	CDD:238113	92/245 (38%)
AgaP_AGAP008649	XP_314746.4	Tryp_SPc	60..287	CDD:214473	92/246 (37%)
AgaP_AGAP008649	XP_314746.4	Tryp_SPc	61..290	CDD:238113	94/247 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910