DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CLIPC3

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_313589.2	Gene:	CLIPC3 / 1274461	VectorBaseID:	AGAP004318	Length:	393	Species:	Anopheles gambiae

Alignment Length:	346	Identity:	108/346 - (31%)
Similarity:	167/346 - (48%)	Gaps:	68/346 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 VCQNKGTQ--VCCPTGQ-------GITNTTPAPSQ-------IVPKNTDE--------------- 239
            ||....|:  ||||..|       |.:..||..||       |..|..:|
Mosquito    62 VCSYSATEAIVCCPQSQQLDSPPSGFSIPTPLNSQSRGGSERISEKKCNEYKDLTTESVAISALT 126

  Fly   240 IPRRLLNVE-EGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGS-PFKCGGTLITARHVLT 302
            :...|:.:: ..|...|   |.||||.|::.|.:|.:|.:|:..|:|. .|.|||:||:..:|||
Mosquito   127 LNPTLVKIDVPKCEMVV---KLIVGGNVTKPGEFPHMAAIGWRQPNGGYSFDCGGSLISEYYVLT 188

  Fly   303 AAHCIRQDL-----QFVRLGEHDLSTDTETGHVD-INIARYVSHPDYNRRNGR-SDMAILYLERN 360
            ||||..:..     ..|||||..|..:.:....: .:|.|::.|||..|..|: :|:|::.|...
Mosquito   189 AAHCYAESADGTLPSIVRLGEQSLVREDDGAEPENYDILRFIVHPDLKRSVGKYNDIALIQLTER 253

  Fly   361 VEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAK 425
            |.||:.|.|.||..:..|..::.:     ..|:|:|...|..:..|.::.:.||:|::|.:.|
Mosquito   254 VIFTNFIRPACLYPSEVLNVRTAI-----ATGFGRTEYLGAKSDELRKVALNIYNNELCAERY-- 311

  Fly   426 EKRYFSADQFDKAV--------LCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGI 482
                    ::|:.:        :|.|.|:||||||||||||||.: ...:....||::||.|.|.
Mosquito   312 --------RYDRHLRQGILSTQMCVGDLAGGKDTCQGDSGGPLQV-TVQENHCMFYILGVTSLGQ 367

  Fly   483 GCARPNVPGVYSSTQYFMDWI 503
            .|. .:.|.:|:....::|||
Mosquito   368 VCG-SSTPAIYTKVHPYLDWI 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	4/11 (36%)
		Tryp_SPc	260..503	CDD:214473	86/258 (33%)
		Tryp_SPc	261..503	CDD:238113	86/257 (33%)
CLIPC3	XP_313589.2	Tryp_SPc	146..390	CDD:238113	88/259 (34%)
CLIPC3	XP_313589.2	Tryp_SPc	146..387	CDD:214473	86/257 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910