DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CLIPC2

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_313588.3	Gene:	CLIPC2 / 1274460	VectorBaseID:	AGAP004317	Length:	383	Species:	Anopheles gambiae

Alignment Length:	352	Identity:	109/352 - (30%)
Similarity:	163/352 - (46%)	Gaps:	45/352 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 KPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQ--VCCPTG-----QGITNTTP 227
            :||.|.....|..||.:.|...              :|.....|  ||||..     |.:.:
Mosquito    40 EPGICQGYNLCRPLLEKSRIVK--------------ICGYTSQQAVVCCPLDYRERLQQLND--- 87

  Fly   228 APSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKK----------IVGGEVSRKGAWPWIALLGYDD 282
             |:|............||......||:|...|.          ||||..:|.|.:|.:|.|...|
Mosquito    88 -PNQRCRDYQSASNSGLLFGSLAVGSSVVKLKPRAQCPTDQNLIVGGTAARFGEFPHMARLAMPD 151

  Fly   283 PSGS-PFKCGGTLITARHVLTAAHCIRQDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRR 346
            .:|: .|:||.|||:.:.|:|||||:......|||||.....|.....||:.:.|.|.||:|..|
Mosquito   152 ENGAMVFRCGATLISEQWVMTAAHCLESQTIVVRLGELKEGNDEFGDPVDVQVTRIVKHPNYKPR 216

  Fly   347 NGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQI 411
            ...:|:|:|.|.|.|.|:.:|.|.||..::.:.:...|     ..|:|.|...|.:::.|.::.:
Mosquito   217 TVYNDIALLKLARPVTFSMRIRPACLYGSSTVDRTKAV-----AIGFGSTEAYGAASKELLKVSL 276

  Fly   412 PIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIG 476
            .::....|...:.:.:|.  .....::.||||.||||:|||.|||||||.:....:..:. .:||
Mosquito   277 DVFTTAACSVFFQRNRRV--PQGLRESHLCAGFLSGGRDTCTGDSGGPLQISSEDEACVA-QIIG 338

  Fly   477 VVSYGIGCARPNVPGVYSSTQYFMDWI 503
            :.|:||||. ...||:|:....::|||
Mosquito   339 ITSFGIGCG-STTPGIYTRVSEYIDWI 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	10/47 (21%)
		Tryp_SPc	260..503	CDD:214473	85/253 (34%)
		Tryp_SPc	261..503	CDD:238113	85/242 (35%)
CLIPC2	XP_313588.3	Tryp_SPc	130..367	CDD:238113	87/244 (36%)
CLIPC2	XP_313588.3	Tryp_SPc	130..364	CDD:214473	85/242 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910