DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP003626

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_313388.5	Gene:	AgaP_AGAP003626 / 1274290	VectorBaseID:	AGAP003626	Length:	305	Species:	Anopheles gambiae

Alignment Length:	312	Identity:	80/312 - (25%)
Similarity:	127/312 - (40%)	Gaps:	45/312 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 LRASNAVCQNKGTQVCCPTGQGI--TNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIV 262
            ||.:...||.....:.....:.|  ||....|...:|....|.|.::
Mosquito    24 LRLAEQKCQEYRKTIASFPSKVIDRTNVFDTPPNGLPAREGEFPHQV------------------ 70

  Fly   263 GGEVSRKGAWPWIALLGYDDPSGSPF--KCGGTLITARHVLTAAHCI-RQDLQFVRLGEHDLSTD 324
                 |.|.|      .|:|...:.|  :|.|.||:.|:||.||||: ....:.|.||.||.:.:
Mosquito    71 -----RVGQW------FYEDEDDTAFILRCSGALISDRYVLIAAHCLWTLGDEEVSLGRHDYTRN 124

  Fly   325 TETGHVDINIARYVSHPDYNRRNGRS--DMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYM 387
            .....:.|.....:.||.|:.:...|  |:|::.|.:.|.|||.|.|.||.......:.:.:...
Mosquito   125 GTFPELSIKRDDLILHPSYDEQTKASYNDIALVRLAQPVTFTSHIYPACLWTEEEAAEPTKLTSS 189

  Fly   388 PFVAG-WGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDT 451
            .|..| .||..:     ..|.::|:....|..|.:.|. :..|:.....| |:|||......|..
Mosquito   190 GFTMGRLGKLRD-----TRLVKIQVSRVPNAECSREYT-DSGYYPQGVTD-ALLCAESPVEWKSL 247

  Fly   452 CQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
            |:||:||.|...:.....: :.||||.:.|..|.:.:...:::..:..:|||
Mosquito   248 CEGDAGGLLQTLDRDSADV-YRLIGVEAKGHECDQSHQKFIFTKVRQQLDWI 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	4/15 (27%)
		Tryp_SPc	260..503	CDD:214473	67/248 (27%)
		Tryp_SPc	261..503	CDD:238113	67/247 (27%)
AgaP_AGAP003626	XP_313388.5	Tryp_SPc	57..301	CDD:238113	72/279 (26%)
AgaP_AGAP003626	XP_313388.5	Tryp_SPc	57..298	CDD:214473	70/277 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910