DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP003248

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_312959.4	Gene:	AgaP_AGAP003248 / 1273921	VectorBaseID:	AGAP003248	Length:	296	Species:	Anopheles gambiae

Alignment Length:	306	Identity:	91/306 - (29%)
Similarity:	148/306 - (48%)	Gaps:	59/306 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 TPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGS-PFK 289
            |||...::|:            ...||:...  ::::...|::....||:||:.|..|:|| .:.
Mosquito    27 TPAQKSLLPQ------------PPMCGNDAP--ERLITSLVAQLDEAPWMALIEYWKPNGSLSYL 77

  Fly   290 CGGTLITARHVLTAAHCIRQ-----DLQFVRLGEHDLSTDTETGH-------VDINIARYVSHPD 342
            |||:||..|:|:|||||:..     .:..:||||.||||..:..|       :|:.:.:...|.|
Mosquito    78 CGGSLINERYVVTAAHCVTSLPQGWTVHRIRLGEWDLSTSEDCDHSRCNDAPIDVAVDKITVHED 142

  Fly   343 YN--RRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSY-----VGYMPFVAGWGKTMEGG 400
            |.  .||.|:|:|::.|:|.:.:|..:||||||....|:.:.|     ||::.  ..:|..  ||
Mosquito   143 YKSPSRNHRNDIALIRLDRQMHYTETVAPICLPQNGPLQTQRYRTMHSVGWIE--ENFGPI--GG 203

  Fly   401 ESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEP 465
            :..||..:|    .|.:.|..:|.:.....:..|     ||   ::..||.....:|||||  :.
Mosquito   204 KKLQVEQDL----VDFQNCSSNYLQASIALADTQ-----LC---VAQQKDNRIDIAGGPLM--QR 254

  Fly   466 YQGQLRFYLIGVVSYG---IGCARPNVPGVYSSTQYFMDWIIQQVQ 508
            ..|  .:||.||.|:|   .|..  .:|.||::...::|||...::
Mosquito   255 IAG--HWYLFGVASFGGRNYGTV--ELPNVYTNVMEYVDWIESNIE 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	83/265 (31%)
		Tryp_SPc	261..503	CDD:238113	83/264 (31%)
AgaP_AGAP003248	XP_312959.4	Tryp_SPc	53..291	CDD:214473	83/259 (32%)
AgaP_AGAP003248	XP_312959.4	Tryp_SPc	54..294	CDD:238113	84/261 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	3	2.920