DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CLIPB2

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_312956.3	Gene:	CLIPB2 / 1273920	VectorBaseID:	AGAP003246	Length:	355	Species:	Anopheles gambiae

Alignment Length:	365	Identity:	131/365 - (35%)
Similarity:	183/365 - (50%)	Gaps:	47/365 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 RGTVCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQVCCPTGQGITN 224
            :|..|..|..:.|.||.::||||||.....|........||.:|......:.|.|||.:.|. |.
Mosquito    22 QGQRCVNPARQTGKCVLVRECASLLAIYSKRFTTPEETQFLASSRCGEIGRKTLVCCASEQQ-TR 85

  Fly   225 TTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGS-PF 288
            |:..|:.  |:               ||..|  ..:|:||:.:....:||.||:.|..|... .|
Mosquito    86 TSSFPTS--PE---------------CGIQV--TDRIIGGQTTELEEFPWTALIEYRKPGNQYDF 131

  Fly   289 KCGGTLITARHVLTAAHCIRQ-----DLQFVRLGEHDLSTDTE-------TGHVDINIARYVSHP 341
            .|||.||.||::||||||::.     .|..|||||.||||..:       .|.:|:.|..:|:|.
Mosquito   132 HCGGALINARYILTAAHCVQSLPRGWQLNGVRLGEWDLSTANDCSDGICSAGPIDLEIESFVAHA 196

  Fly   342 DYNRRN--GRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQ 404
            .|:..:  ..:|:|::.|.::|..:..|.|||||.|...|.::.||.:.|.||||||.....|.:
Mosquito   197 GYDAADTAHTNDIALIRLRQDVASSEMIRPICLPLTEPQRSRNRVGTVSFAAGWGKTESASASER 261

  Fly   405 VLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQ 469
            .| ::::.:.|...|.|.|........|.|     :|||.|. |||||.||||||||.    :..
Mosquito   262 KL-KVELTVQDPSRCRQIYRGINIALKASQ-----MCAGGLQ-GKDTCTGDSGGPLMA----KSA 315

  Fly   470 LRFYLIGVVSYGIG-CARPNVPGVYSSTQYFMDWIIQQVQ 508
            ..:|||||||:|:. |.....||||::...::|||...||
Mosquito   316 GAWYLIGVVSFGLSKCGTAGYPGVYTNVVEYLDWIESNVQ 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	17/51 (33%)
		Tryp_SPc	260..503	CDD:214473	99/258 (38%)
		Tryp_SPc	261..503	CDD:238113	99/257 (39%)
CLIPB2	XP_312956.3	CLIP	26..78	CDD:288855	17/51 (33%)
		Tryp_SPc	102..350	CDD:214473	99/258 (38%)
		Tryp_SPc	103..353	CDD:238113	101/260 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	3	2.920