DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CLIPB8

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_312743.1	Gene:	CLIPB8 / 1273740	VectorBaseID:	AGAP003057	Length:	405	Species:	Anopheles gambiae

Alignment Length:	392	Identity:	114/392 - (29%)
Similarity:	185/392 - (47%)	Gaps:	51/392 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 APIPDTSAAPLIEPRGTVCRGP-DTKPGNCVEIKECASL--LNELRSRSQDATFANFLRASNAVC 207
            ||: ||...|:.:.. .:|..| :..||.|:...||.:.  :|::.|.|....| :|::  ...|
Mosquito    25 APM-DTDDRPVWDSI-RLCDIPNEPNPGQCMLPAECVAYGKINDVSSLSSIERF-SFIK--QIQC 84

  Fly   208 QNKGT--QVCCPTGQGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKG 270
            ....|  .||||..............:||||  .:..|:....:.|| ...|..||.||:::...
Mosquito    85 NGSDTVPYVCCPRDSDAYREPYVNETMVPKN--RVASRIAFDADSCG-IQSYVAKIRGGQLAEID 146

  Fly   271 AWPWIALLGYD-DPSGSPFKCGGTLITARHVLTAAHCI--------RQDLQFVRLGEHDLST--- 323
            .:||:|:|.|: |.:.....|||.||:..:|:|||||:        :..|:||||.|:::.|
Mosquito   147 EFPWMAMLLYERDNNALTQGCGGALISRTYVITAAHCVTGKNFQQTKGRLKFVRLREYNIHTNPD 211

  Fly   324 --------DTETGHVDINIARYVSHPDYNRR--NGRSDMAILYLERNVEFTSKIAPICLPHTANL 378
                    |.....:|:.....:.||:|:..  |.:.|:|::.:|:...||..:..||||. .|.
Mosquito   212 CVYENDLKDCSDDMIDLVPQAVIPHPEYDSESSNQQHDIALIRIEQTPPFTDFLRSICLPE-QNF 275

  Fly   379 RQKSYVGYMPFVAGWGKT--MEGGESAQVLN----ELQIPIYDNKVCVQSYAKEKRYFSADQFDK 437
            ...:..|....|:|||:|  .:......||:    :|.:|..:.:.|.:::..........|
Mosquito   276 ESSATPGKKLSVSGWGRTDIFKDNLGPDVLSPIKLKLSLPYVEREKCSKTFRPWSFALGPGQ--- 337

  Fly   438 AVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGI-GCARPNVPGVYSSTQYFMD 501
              :|||. ...||||.||||.|||..:  ..:..:|:.|:||.|: ||....:||||::..:::.
Mosquito   338 --MCAGG-ERAKDTCAGDSGSPLMSYD--MKRAIWYITGIVSLGVRGCGVEGLPGVYTNVHHYLP 397

  Fly   502 WI 503
            ||
Mosquito   398 WI 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	15/56 (27%)
		Tryp_SPc	260..503	CDD:214473	81/271 (30%)
		Tryp_SPc	261..503	CDD:238113	80/270 (30%)
CLIPB8	XP_312743.1	CLIP	41..95	CDD:288855	15/56 (27%)
		Tryp_SPc	136..399	CDD:214473	81/271 (30%)
		Tryp_SPc	139..400	CDD:238113	81/270 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	3	2.920