DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP010635

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_307830.4	Gene:	AgaP_AGAP010635 / 1269219	VectorBaseID:	AGAP010635	Length:	569	Species:	Anopheles gambiae

Alignment Length:	308	Identity:	88/308 - (28%)
Similarity:	132/308 - (42%)	Gaps:	60/308 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 QIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFK--CGGT 293
            :|...|.:|...||:..:|          .:.||..:..|.|||.|.|.:...:...|:  ||.|
Mosquito    28 EIYDYNDNECGERLVKRQE----------LVKGGYSTHPGDWPWHAALYHRGFNSRDFEYACGST 82

  Fly   294 LITARHVLTAAHC---------IRQDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGR 349
            ::....|:|||||         |..|...:|||..:|..:.|....:.::...:.|..|......
Mosquito    83 IVHRYLVITAAHCVTFATSRRKIPSDNMQLRLGRFNLMNNEEEYAEEFSVIDTIVHEGYRPTTLE 147

  Fly   350 SDMAILYLERNVEFTSKIAPIC---------LPHTANLRQKSYVGYMP-FVAGWGKTMEGGESAQ 404
            :|:|||.:|..:.|...|.|:|         ||:..|         .| .|.|||.: |......
Mosquito   148 NDIAILRVEIPIIFNDYIQPVCLWKRDDGFDLPNVYN---------QPGTVVGWGLS-ENNRIGT 202

  Fly   405 VLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQ 469
            .|||.|:|:.::..|:   |.::.:|......|| .||| ...|...|.|||||.:.    :|.|
Mosquito   203 TLNEAQMPVVNSWTCL---ASDRAFFGRFLQSKA-FCAG-YKNGTGVCNGDSGGGMF----FQFQ 258

  Fly   470 LRFYLIGVVS------YGIGCARPNVPGVYSSTQYFMDWIIQQVQDTP 511
            .|:||.|:||      |...|......|...::|| :||:   .::||
Mosquito   259 NRWYLKGIVSFSSVNDYSGWCNLRQYIGFTDASQY-IDWV---YENTP 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	79/269 (29%)
		Tryp_SPc	261..503	CDD:238113	79/268 (29%)
AgaP_AGAP010635	XP_307830.4	Tryp_SPc	50..300	CDD:238113	80/272 (29%)
		Tryp_SPc	50..297	CDD:214473	79/266 (30%)
		Tryp_SPc	342..563	CDD:214473
		Tryp_SPc	342..563	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910