DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and AgaP_AGAP012473

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_307308.4	Gene:	AgaP_AGAP012473 / 1268739	VectorBaseID:	AGAP012473	Length:	272	Species:	Anopheles gambiae

Alignment Length:	325	Identity:	86/325 - (26%)
Similarity:	128/325 - (39%)	Gaps:	92/325 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 LRASNAVCQNKGTQVCCPTGQGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGG 264
            |...|||..|...|                      ||.|.|.....:..|....:..:|..:..
Mosquito    12 LFCGNAVVTNANVQ----------------------NTKEGPSHSGRIVNGVPVNISNYKYALSM 54

  Fly   265 EVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI------RQDLQFVRLGEHDLST 323
            .::                  ..|:||.::||..|.|:||||:      |     :.|..:..||
Mosquito    55 RLN------------------GEFRCGASIITCSHALSAAHCVYNLTGPR-----IELTLYGGST 96

  Fly   324 DTETGHVDINIARYVSHPDYNRRNGRS-----DMAILYLERNVEFTSK--IAPICLPHTANLRQK 381
            ...:|.|:..:.....|| |.:.|.:|     |:|||.:..| .|:.:  :||:.| .|..|.
Mosquito    97 SASSGGVEFPVVGGAIHP-YYKPNSQSNTSDYDVAILNVPAN-SFSGRPNMAPLAL-QTKELP-- 156

  Fly   382 SYVGYMPFVAGWGKTMEGGESAQV-LNEL---QIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCA 442
              ||...||.|||:|   ||:..| .|:|   .:.|.....|...:|..::..:.   .|.::||
Mosquito   157 --VGTRCFVVGWGRT---GENQPVSTNQLLYANMNIVSQSSCASMWANFEKLCAE---CKHMVCA 213

  Fly   443 GVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGC--------ARPNVPGVYSSTQYF 499
            ...: |.|||:|||||.|:.    .|:    |.||||:|..|        |:...|.:.|..|.:
Mosquito   214 QYYN-GMDTCRGDSGGALVC----GGR----LTGVVSFGPYCSGVWPSVFAKVTAPSMRSFIQLY 269

Fly 500 499
Mosquito 270 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	6/15 (40%)
		Tryp_SPc	260..503	CDD:214473	74/265 (28%)
		Tryp_SPc	261..503	CDD:238113	74/264 (28%)
AgaP_AGAP012473	XP_307308.4	Tryp_SPc	36..266	CDD:214473	75/274 (27%)
AgaP_AGAP012473	XP_307308.4	Tryp_SPc	37..267	CDD:238113	75/274 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910