DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Cfi

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_031712.2	Gene:	Cfi / 12630	MGIID:	105937	Length:	603	Species:	Mus musculus

Alignment Length:	438	Identity:	104/438 - (23%)
Similarity:	170/438 - (38%)	Gaps:	129/438 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 CRGPDTKPGNCVEIKECASLLNELRS---RSQDATFANFL-------------RASNAV--CQNK 210
            |||.:|....|...|....|.|.|..   ..|||.|...|             :|.|.|  |.::
Mouse   191 CRGVETSLAECAFTKRRTELSNGLAGVVCYKQDADFPTSLSFQCVNGKHIPQEKACNGVNDCGDQ 255

  Fly   211 GTQVCCP----------------------------TGQ---------------GITNTTPAPSQI 232
            ..::||.                            ||:               |:..:....::|
Mouse   256 SDELCCKGCRGNASLCKSGVCIPDQYKCNGEVDCITGEDESRCEEDRQQNIPKGLARSAQGEAEI 320

  Fly   233 VPKNTDEIPRRLLNVEE---------GCG---STVGYFKKIVGGEVSRKGAWPW-IALLGYDDPS 284
            ..:.|:.:...:.|..:         .||   :|....|:::||:.:..|.:|| :|:     ..
Mouse   321 ETEETEMLTPGMDNERKRIKSLLPKLSCGVKRNTHTRRKRVIGGKPANVGDYPWQVAI-----KD 380

  Fly   285 GSPFKCGGTLITARHVLTAAHCIRQDLQFVRLGEHD--------LSTDTETGHVDINIARYVSHP 341
            |....|||..|....:||||||:|..    |...:.        |..:::.|..  .:.|.:.|.
Mouse   381 GQRITCGGIYIGGCWILTAAHCVRPS----RAHSYQVWTALLDWLKPNSQLGIQ--TVKRVIVHE 439

  Fly   342 DYNRRNGRSDMAILYL-----ERNVEFTSKIAPICLPHTANLRQKSYVGYMP----FVAGWGKTM 397
            .||....::|:|::.:     ::..|..:.: |.|:|.:..|       :.|    .::|||:
Mouse   440 KYNGATFQNDIALIEMKMHTGKKECELPNSV-PACVPWSPYL-------FQPNDRCIISGWGR-- 494

  Fly   398 EGGESAQVLNEL---QIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGP 459
              |:..|.:..|   ::.:..|  |.|.|  ..||     ::|.:.|||...|..|.|:||||||
Mouse   495 --GKDNQKVYSLRWGEVDLIGN--CSQFY--PDRY-----YEKEMQCAGTRDGSIDACKGDSGGP 548

  Fly   460 LMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQV 507
            |:..:.....   |:.|:||:|..|.:|..||||:....:.|||...|
Mouse   549 LVCEDINNVT---YVWGIVSWGENCGKPEFPGVYTRVANYFDWISYHV 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	18/69 (26%)
		Tryp_SPc	260..503	CDD:214473	71/263 (27%)
		Tryp_SPc	261..503	CDD:238113	71/262 (27%)
Cfi	NP_031712.2	FIMAC	46..111	CDD:214493
		SR	117..220	CDD:214555	9/28 (32%)
		SRCR	122..219	CDD:278931	9/27 (33%)
		LDLa	232..261	CDD:238060	4/28 (14%)
		LDLa	264..298	CDD:294076	2/33 (6%)
		Tryp_SPc	360..589	CDD:214473	71/263 (27%)
		Tryp_SPc	361..592	CDD:238113	73/265 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910