DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and Prss29

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_444490.2	Gene:	Prss29 / 114662	MGIID:	2149952	Length:	279	Species:	Mus musculus

Alignment Length:	301	Identity:	98/301 - (32%)
Similarity:	147/301 - (48%)	Gaps:	61/301 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 TPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPW-IALLGYDDPSGSPF- 288
            ||||.   |:                    |....||||..:.:|.||| ::|..|      .:
Mouse    19 TPAPG---PE--------------------GVLMGIVGGHSAPQGKWPWQVSLRIY------RYY 54

  Fly   289 ------KCGGTLITARHVLTAAHCIRQ-----DLQFVRLGEHDLSTDTETGHVDINIARYVSHPD 342
                  .|||::|..:.|||||||||:     .:..:|:||..|....|.    ::::|.:.|||
Mouse    55 WAFWVHNCGGSIIHPQWVLTAAHCIRERDADPSVFRIRVGEAYLYGGKEL----LSVSRVIIHPD 115

  Fly   343 YNRRNGRSDMAILYLERNVEFTSKIAPICLP-HTANLRQKSYVGYMPFVAGWG--KTMEGGESAQ 404
            :......||:|:|.|..:|:....:.|:.|| .:..:.:|.    :.:|.|||  .|........
Mouse   116 FVHAGLGSDVALLQLAVSVQSFPNVKPVKLPSESLEVTKKD----VCWVTGWGAVSTHRSLPPPY 176

  Fly   405 VLNELQIPIYDNKVCVQSYAKEKRYFSADQ--FDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQ 467
            .|.::|:.|.||.:|.:.|....|:.:..|  ..|.:||||  :.|:|:|.|||||||:.  ...
Mouse   177 RLQQVQVKIIDNSLCEEMYHNATRHRNRGQKLILKDMLCAG--NQGQDSCYGDSGGPLVC--NVT 237

  Fly   468 GQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQ 508
            |.  :.|:||||:|.|||..:.||||:..|.|:.||.||:|
Mouse   238 GS--WTLVGVVSWGYGCALRDFPGVYARVQSFLPWITQQMQ 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	87/260 (33%)
		Tryp_SPc	261..503	CDD:238113	87/259 (34%)
Prss29	NP_444490.2	Tryp_SPc	31..274	CDD:238113	89/262 (34%)
Prss29	NP_444490.2	Tryp_SPc	31..271	CDD:214473	87/259 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910