DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and f7

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	322	Identity:	98/322 - (30%)
Similarity:	149/322 - (46%)	Gaps:	45/322 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 NKGTQVCCPTGQGITNTTPAPS-------------QIVPKNTDEIPRRLLNVEEGCGSTVGYFKK 260
            |.|.:..|....|..|.:.|..             ::.|  ..::|  ||...:.....|....:
Zfish   135 NGGCEHFCTEQDGRRNCSCADGYYLDNGGQKCRSHEVFP--CGKVP--LLQAGKAADHQVDLRSR 195

  Fly   261 IVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQ-DLQFVRL--GEHDLS 322
            ||||....||..||..||.|    |....|||.:.....:||||||:.: .::|:|:  |||||.
Zfish   196 IVGGSECPKGHCPWQVLLKY----GEKGFCGGVIYKPTWILTAAHCLEKLKVKFLRIVAGEHDLE 256

  Fly   323 TDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYM 387
            .|..|..: |.:.:..:||.|......||:|:|.|...:.::....|:|||......::.:....
Zfish   257 VDEGTEQL-IQVDQMFTHPAYVSETADSDIALLRLRTPIVYSVYAVPVCLPLREMAERELWAVSK 320

  Fly   388 PFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTC 452
            ..|:||||..|.|.::::|..|.:|....:.|||        .|.......:.|||.:.|.:|:|
Zfish   321 HTVSGWGKRSEDGPTSRLLRRLLVPRIRTQECVQ--------VSNLTLTSNMFCAGYIEGRQDSC 377

  Fly   453 QGDSGGPLMLPEPYQGQLRF----YLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQDT 510
            :|||||||:        .|:    :|:|:||:|.|||||...|:|:....::.||.|....|
Zfish   378 KGDSGGPLV--------TRYRDTAFLLGIVSWGKGCARPGSYGIYTRVSNYLQWIRQTTNTT 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	2/6 (33%)
		Tryp_SPc	260..503	CDD:214473	83/249 (33%)
		Tryp_SPc	261..503	CDD:238113	83/248 (33%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011
		FXa_inhibition	131..166	CDD:291342	6/30 (20%)
		Tryp_SPc	195..424	CDD:214473	83/249 (33%)
		Tryp_SPc	196..427	CDD:238113	85/251 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910