DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and AgaP_AGAP013487

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_003436426.1	Gene:	AgaP_AGAP013487 / 11176153	VectorBaseID:	AGAP013487	Length:	308	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	92/285 - (32%)
Similarity:	153/285 - (53%)	Gaps:	34/285 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 KNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGS-PFKCGGTLITAR 298
            :||..:|.     ...||..:|  .:::.|:.::...:||.||:.:..|.|| .|.|||:||..|
Mosquito    37 QNTSSLPE-----SPHCGIQLG--DRVLSGQSTQIDEFPWTALIEFQKPDGSFGFHCGGSLINDR 94

  Fly   299 HVLTAAHCIRQ-----DLQFVRLGEHDLSTDTETGH-------VDINIARYVSHPDYNR--RNGR 349
            :::||||||:.     .:|.|||||.||::..:..:       :|::|.:.|.|..|:.  ::..
Mosquito    95 YIVTAAHCIKSIPRDWKVQRVRLGEWDLTSANDCQNEFCSDAPIDLDIEQIVVHTGYDTKDKSNA 159

  Fly   350 SDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIY 414
            :|:|::...|.|.::..:.|||||.:::||.:|:.|.:.:..||.||.....|.:.| ::::.|.
Mosquito   160 NDIALIRFTRPVNYSQTVRPICLPLSSSLRNRSHDGLISYEVGWRKTNSATASEKKL-KVEVEIK 223

  Fly   415 DNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVS 479
            ..:.|...|.:     :.....:..:|||.:. .||||.|:||||||    .|....:|||||.|
Mosquito   224 SLQECAPIYER-----NGILLKQTHMCAGGVR-SKDTCSGNSGGPLM----RQMTGSWYLIGVNS 278

  Fly   480 YG-IGCARPNVPGVYSSTQYFMDWI 503
            :| ..|....||.||::...::|||
Mosquito   279 FGPRKCGTFGVPDVYTNVAEYVDWI 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	84/258 (33%)
		Tryp_SPc	261..503	CDD:238113	84/257 (33%)
AgaP_AGAP013487	XP_003436426.1	Tryp_SPc	55..303	CDD:214473	84/258 (33%)
AgaP_AGAP013487	XP_003436426.1	Tryp_SPc	59..306	CDD:238113	86/256 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	3	2.920