DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CLIPB36

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_003436427.1	Gene:	CLIPB36 / 11175953	VectorBaseID:	AGAP013184	Length:	394	Species:	Anopheles gambiae

Alignment Length:	381	Identity:	101/381 - (26%)
Similarity:	154/381 - (40%)	Gaps:	73/381 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 VCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKG-TQVCCPTGQGITNTT 226
            :|...:.:.|.||.:|:|.|::..||..:.......:|..:......:| ..||||....:....
Mosquito    36 LCITEEQQRGRCVPVKQCDSVMTTLRKDTLTPEDIQYLYGTECGRTAEGKALVCCPQSSLVPVGG 100

  Fly   227 PAPSQIVPKNTDEIPRRLLNVEE-------------GCG--STVGYFKKIVGGEVSRKGAWPWIA 276
            |..|.|   ||    ...:|.||             .||  |.|......:|..       ||..
Mosquito   101 PMESGI---NT----TIRVNAEEKQPTEPTLEVAPNACGLQSAVKLTNLTIGHH-------PWTV 151

  Fly   277 LLGYDDPSGS-PFKCGGTLITARHVLTAAHCIRQDLQF----VRLGEHDLST------DTETGHV 330
            ||.|...:.| .|.|.||||...:|||:|.|:..:..:    |||||.||.:      |.::..:
Mosquito   152 LLHYGGQAHSTQFNCSGTLIAPSYVLTSASCVDDEAAWNNLTVRLGEWDLESTVDCILDPDSDDL 216

  Fly   331 -------DINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMP 388
                   |:.:.:.:.|..|..|  |:|:|:|.|.:..:....::|||||.:..|.:.:..|
Mosquito   217 VCADPSYDVPVGQVILHEAYTGR--RNDIALLKLAQPAQLNDWVSPICLPESPVLNETAKYG--- 276

  Fly   389 FVAGWGKTMEGGESAQVLNELQIPIYD---NKVCVQSYAKEKRYF-SADQFDKAVLCAGVLSGGK 449
             .|||.:......|::.   .|:..||   .|.|       :||. |........:|..|   |:
Mosquito   277 -AAGWNQNTCADPSSRY---KQLSSYDALNQKAC-------ERYVPSVAGTSYGFVCVAV---GE 327

  Fly   450 DTCQGDSGGPLMLPEPYQ--GQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
            :...||:||.|.......  |:....|:||:|....||......||:....::|||
Mosquito   328 EQPLGDAGGGLTAVRTIDSAGRSVHELVGVLSSLSSCANFQGVSVYTRVAQYVDWI 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	12/52 (23%)
		Tryp_SPc	260..503	CDD:214473	72/266 (27%)
		Tryp_SPc	261..503	CDD:238113	72/265 (27%)
CLIPB36	XP_003436427.1	CLIP	37..90	CDD:288855	12/52 (23%)
		Tryp_SPc	143..386	CDD:238113	74/267 (28%)
		Tryp_SPc	143..383	CDD:214473	72/265 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	3	2.920