DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Prss48

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_017446782.1	Gene:	Prss48 / 108350052	RGDID:	11436036	Length:	308	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	97/262 - (37%)
Similarity:	139/262 - (53%)	Gaps:	30/262 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 CGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQD----L 311
            ||..| |..:||||:.:..|.|||...|.:|    |...|||:||:...|:||||||::.    |
  Rat    31 CGRPV-YSGRIVGGQGAALGHWPWQVSLRFD----STHICGGSLISNHWVMTAAHCIKKTWFSFL 90

  Fly   312 QFVRLG--EHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPH 374
            ..|.||  :.|.|:..|    :..::|.|....::..:|  |:|:|.|...|.|||.:.|||||
  Rat    91 YSVWLGSIDRDYSSTGE----EYYVSRIVIPSKHHNTDG--DIALLKLSSRVTFTSLVLPICLP- 148

  Fly   375 TANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQ---FD 436
              |:.:...|....:|.|||:..| |.....|.||::||...:.|.|.| ....:|..|.   ..
  Rat   149 --NISKPLTVPASCWVTGWGQNQE-GHYPSTLQELEVPIITGEACEQLY-NPIGFFLPDLERIIK 209

  Fly   437 KAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMD 501
            :.:||||.:...||:|:|||||||..  ...|.  :..|||:|:|:.|.: |:||||::..|:..
  Rat   210 EDMLCAGEIQQSKDSCKGDSGGPLSC--HIDGV--WTQIGVISWGLECGK-NLPGVYTNVTYYQK 269

  Fly   502 WI 503
            ||
  Rat   270 WI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	91/251 (36%)
		Tryp_SPc	261..503	CDD:238113	91/250 (36%)
Prss48	XP_017446782.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910