DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and prss56

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_017949880.1	Gene:	prss56 / 101731690	XenbaseID:	XB-GENE-6051085	Length:	665	Species:	Xenopus tropicalis

Alignment Length:	348	Identity:	101/348 - (29%)
Similarity:	162/348 - (46%)	Gaps:	71/348 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 GNC-VEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQVCCPTGQ---GITNTTPAPSQI 232
            |.| ::::||...:|           .::|..|    .:.|:.|.|  ||   .|:|.|.
Frog    28 GRCQLKLEECKLEMN-----------MDYLNTS----PDDGSPVTC--GQKFSSISNNTG----- 70

  Fly   233 VPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITA 297
             ||.                       :||||.::..|:|||:..:.::    ....|||.|:..
Frog    71 -PKG-----------------------RIVGGSITSPGSWPWLVNIRFN----GELMCGGVLLDD 107

  Fly   298 RHVLTAAHC----IRQDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLE 358
            ..:||||||    :.:.|..|.:|::||:.:.: |.....:.|.|:||.:|::...:|:|:|.|.
Frog   108 MWILTAAHCFTGSVNEVLWTVVVGQYDLTKNAQ-GEKTFQVNRIVTHPKFNQKTFDNDLALLELT 171

  Fly   359 RNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSY 423
            .:|..:....|:|||   .:.:....|...::||||...|.|..:.|:.|.::|:...:.|..:.
Frog   172 SSVTASQSARPVCLP---PVPRDPTPGTNCYIAGWGSLYEDGPLSDVIMEARVPVLSQEACRSTL 233

  Fly   424 AKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPN 488
            .|       :.....:.|||.|:||.|:|||||||||...:|...|  :.|.|:.|:|.||....
Frog   234 GK-------NMLTSTMFCAGYLNGGIDSCQGDSGGPLTCQDPISKQ--YVLYGITSWGDGCGERG 289

  Fly   489 VPGVYSSTQYFMDWIIQQVQDTP 511
            .||||:....|.|||..|:..:|
Frog   290 KPGVYTRVTAFTDWISHQMNKSP 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	9/44 (20%)
		Tryp_SPc	260..503	CDD:214473	80/246 (33%)
		Tryp_SPc	261..503	CDD:238113	80/245 (33%)
prss56	XP_017949880.1	Tryp_SPc	75..305	CDD:238113	81/246 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910